日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Broadly reactive anti-VHH antibodies for characterizing, blocking, or activating nanobody-based CAR-T cells.

用于表征、阻断或激活基于纳米抗体的 CAR-T 细胞的广谱抗 VHH 抗体

McComb Scott, Dupont Bianca, Shepherd Alex, Bennychen Bigitha, Marcil Anne, Tamblyn Laura, Raphael Shalini, Sheff Joey, Hussack Greg, Moraitis Anna N, Wu Cunle, Aubry Annie, Gadoury Christine, Lippens Julie, Pagé Martine, Fortin Annie, Joubert Simon, Lamoureux Linda, Parat Marie, Plante Pierre, Malenfant Félix, Acchione Mauro, Pohankova Petra, Schrag Joe, Acel Andrea, Coutu Mathieu, Smith Emma, El Bakkouri Majida, Hill Jennifer J, Tremblay Tammy-Lynn, Manceur Aziza P, Faulkes Sharlene, Webb John, Zafer Ahmed, Zhu Qin, Nguyen Tina, Pon Robert A, Weeratna Risini D, Arbabi-Ghahroudi Mehdi

A Flow Cytometry-Based Method for Assessing CAR Cell Binding Kinetics Using Stable CAR Jurkat Cells

使用流式细胞术评估稳定 CAR Jurkat 细胞的 CAR 细胞结合动力学的方法

Alex Shepherd, Bigitha Bennychen, Zafer Ahmed, Risini D Weeratna, Scott McComb

Preclinical development of a vaccine-based immunotherapy regimen (VBIR) that induces potent and durable T cell responses to tumor-associated self-antigens

疫苗型免疫疗法(VBIR)的临床前开发,该疗法可诱导针对肿瘤相关自身抗原的强效且持久的T细胞反应

Cho, Helen; Binder, Joe; Weeratna, Risini; Dermyer, Michael; Dai, Stanley; Boccia, Antionio; Li, Wei; Li, Shangjin; Jooss, Karin; Merson, James; Hollingsworth, Robert E

Identifying effect modifiers of CAR-T cell therapeutic efficacy: a systematic review and individual patient data meta-analysis protocol

识别CAR-T细胞治疗疗效的影响因素:系统评价和个体患者数据荟萃分析方案

Lalu, Manoj M; Kekre, Natasha; Montroy, Joshua; Ghiasi, Maryam; Hay, Kevin; McComb, Scott; Weeratna, Risini; Atkins, Harold; Hutton, Brian; Yahya, Ayel; Masurekar, Ashish; Sobh, Mohamad; Fergusson, Dean A

A simplified function-first method for the discovery and optimization of bispecific immune engaging antibodies

一种简化的功能优先方法,用于发现和优化双特异性免疫接合抗体

Alex Shepherd, Bigitha Bennychen, Anne Marcil, Darin Bloemberg, Robert A Pon, Risini D Weeratna, Scott McComb

Programmable Attenuation of Antigenic Sensitivity for a Nanobody-Based EGFR Chimeric Antigen Receptor Through Hinge Domain Truncation

通过铰链区截短实现基于纳米抗体的EGFR嵌合抗原受体的抗原敏感性可编程衰减

Scott McComb ,Tina Nguyen ,Alex Shepherd ,Kevin A Henry ,Darin Bloemberg ,Anne Marcil ,Susanne Maclean ,Ahmed Zafer ,Rénald Gilbert ,Christine Gadoury ,Robert A Pon ,Traian Sulea ,Qin Zhu ,Risini D Weeratna

Maternal Immune Cell and Cytokine Profiles to Predict Cardiovascular Risk Six Months after Preeclampsia

母体免疫细胞和细胞因子谱预测先兆子痫后六个月的心血管风险

Murphy, Malia S Q; Benton, Samantha J; Cox, Brian; Nerenberg, Kara; McComb, Scott; Krishnan, Lakshmi; Weeratna, Risini D; Paré, Jean-François; Dingwall-Harvey, Alysha L J; Bainbridge, Shannon A; Gruslin, Andrée; Gaudet, Laura M

A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice

一种低剂量腺病毒载体疫苗,表达曼氏血吸虫组织蛋白酶B,可保护小鼠免受肠道血吸虫病的侵害。

Perera, Dilhan J; Hassan, Adam S; Liu, Sunny S; Elahi, Seyyed Mehdy; Gadoury, Christine; Weeratna, Risini D; Gilbert, Rénald; Ndao, Momar

Adjuvanted Schistosoma mansoni-Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model

佐剂型曼氏血吸虫-组织蛋白酶 B 与硫酸化乳糖基古醇古体或 AddaVax™ 可在临床前血吸虫病模型中提供保护

Dilhan J Perera, Adam S Hassan, Yimei Jia, Alessandra Ricciardi, Michael J McCluskie, Risini D Weeratna, Momar Ndao

A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells

一种用于表征 Jurkat 细胞中新型嵌合抗原受体的高通量方法

Darin Bloemberg, Tina Nguyen, Susanne MacLean, Ahmed Zafer, Christine Gadoury, Komal Gurnani, Anindita Chattopadhyay, Josée Ash, Julie Lippens, Doreen Harcus, Martine Pagé, Annie Fortin, Robert A Pon, Rénald Gilbert, Anne Marcil, Risini D Weeratna, Scott McComb