日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The E3-ome gene-centric compendium reveals the human E3 ligase landscape.

以 E3 连接酶组为中心的基因汇编揭示了人类 E3 连接酶的全貌。

Chua Ngee Kiat, González-Robles Tania J, Reddington Cameron J, Dudley-Fraser Jane, Birkinshaw Richard W, Han Jiru, Solano Ashleigh, Wong Soon Wei, Kochańczyk Tomasz, Peter Joshua J, Nakasone Mark A, Aust Florian, Munro Jacob, Tong Yeh Huei, Iskander Julie, Abeysekera Waruni, Garnham Alex, Huckstep Hannah, Ritchie Matthew E, Wertz Ingrid, Hymowitz Sarah, Kumar Sharad, Conaway Ron C, Privé Gilbert G, Bullock Alex N, Babon Jeffrey J, Klevit Rachel E, Lorenz Sonja, Ciulli Alessio, Fischer Eric S, Thomä Nicolas H, Nowak Radosław P, Schulman Brenda A, Rapé Michael, Rittinger Katrin, Pagan Julia K, Bahlo Melanie, Mackay Joel P, Mace Peter D, Lima Christopher D, Hay Ronald T, Komander David, Lechtenberg Bernhard C, Joazeiro Claudio A P, Pagano Michele, Hofmann Kay, Feltham Rebecca

Structure and mechanism of the HECT ligase HECTD3.

HECT连接酶HECTD3的结构和机制。

Huber Jessica, Esposito Diego, Maslen Sarah, Chambers Dominic O, Skehel J Mark, Rittinger Katrin

Identification of RING E3 pseudoligases in the TRIM protein family.

TRIM 蛋白家族中 RING E3 假连接酶的鉴定

Dudley-Fraser Jane, Esposito Diego, McPhie Katherine A, Morley-Williams Coltrane, Auchynnikava Tania, Rittinger Katrin

Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics

使用无标记化学蛋白质组学对半胱氨酸反应片段进行稳健的蛋白质组分析

George S Biggs #, Emma E Cawood #, Aini Vuorinen, William J McCarthy, Harry Wilders, Ioannis G Riziotis, Antonie J van der Zouwen, Jonathan Pettinger, Luke Nightingale, Peiling Chen, Andrew J Powell, David House, Simon J Boulton, J Mark Skehel, Katrin Rittinger, Jacob T Bush

Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination

发现并优化TRIM25的共价配体及其在靶向蛋白质泛素化中的应用

McPhie, Katherine A; Esposito, Diego; Pettinger, Jonathan; Norman, Daniel; Werner, Thilo; Mathieson, Toby; Bush, Jacob T; Rittinger, Katrin

Bacterial effectors mediate kinase reprogramming through mimicry of conserved eukaryotic motifs.

细菌效应蛋白通过模拟保守的真核生物基序来介导激酶重编程

Panagi Ioanna, Muench Janina H, Ronneau Alexi, Diaz-Del-Olmo Ines, Aliyath Agnel, Yu Xiu-Jun, Mak Hazel, Jin Enkai, Zeng Jingkun, Esposito Diego, Jennings Elliott, Pillay Timesh D, Günster Regina A, Maslen Sarah L, Rittinger Katrin, Thurston Teresa L M

Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation

通过化学蛋白质组学筛选和高通量优化进行对映选择性OTUD7B片段发现

Aini Vuorinen # ,Cassandra R Kennedy # ,Katherine A McPhie # ,William McCarthy ,Jonathan Pettinger ,J Mark Skehel ,David House ,Jacob T Bush ,Katrin Rittinger

Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2

共价片段筛选抑制细菌NEL酶SspH1和SspH2的E3连接酶活性

Cassandra R Kennedy ,Katherine A McPhie ,Aini Vuorinen ,Jane Dudley-Fraser ,Diego Esposito ,Sarah Maslen ,William J McCarthy ,Jonathan Pettinger ,J Mark Skehel ,Jacob Bush ,David House ,Katrin Rittinger

Conformational dynamics of the bacterial E3 ligase SspH1

细菌E3连接酶SspH1的构象动力学

Kennedy, Cassandra R; Esposito, Diego; Huber, Jessica; House, David; Rittinger, Katrin

Instinct to insight: a variation-based framework to test hypotheses about how animals solve problems

从本能到顿悟:一个基于变异的框架,用于检验关于动物如何解决问题的假设

Rittinger, Madison A; Rodríguez, Rafael Lucas