日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase

Hedgehog 酰基转移酶抑制剂的设计、合成及评价

Markus Ritzefeld, Leran Zhang, Zhangping Xiao, Sebastian A Andrei, Olivia Boyd, Naoko Masumoto, Ursula R Rodgers, Markus Artelsmair, Lea Sefer, Angela Hayes, Efthymios-Spyridon Gavriil, Florence I Raynaud, Rosemary Burke, Julian Blagg, Henry S Rzepa, Christian Siebold, Anthony I Magee, Thomas Lanyon

Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)*

利用光化学探针鉴定刺猬酰基转移酶 (HHAT) 中的小分子抑制剂结合位点*

Lanyon-Hogg, Thomas; Ritzefeld, Markus; Zhang, Leran; Andrei, Sebastian A; Pogranyi, Balazs; Mondal, Milon; Sefer, Lea; Johnston, Callum D; Coupland, Claire E; Greenfield, Jake L; Newington, Joshua; Fuchter, Matthew J; Magee, Anthony I; Siebold, Christian; Tate, Edward W

Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)

利用光化学探针鉴定刺猬酰基转移酶(HHAT)中的小分子抑制剂结合位点

Lanyon-Hogg, Thomas; Ritzefeld, Markus; Zhang, Leran; Andrei, Sebastian A; Pogranyi, Balazs; Mondal, Milon; Sefer, Lea; Johnston, Callum D; Coupland, Claire E; Greenfield, Jake L; Newington, Joshua; Fuchter, Matthew J; Magee, Anthony I; Siebold, Christian; Tate, Edward W

Correction: Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain

更正:蝙蝠 IFITM3 的限制依赖于 S-棕榈酰化和 CD225 结构域内的多态性位点。

Benfield, Camilla To; MacKenzie, Farrell; Ritzefeld, Markus; Mazzon, Michela; Weston, Stuart; Tate, Edward W; Teo, Boon Han; Smith, Sarah E; Kellam, Paul; Holmes, Edward C; Marsh, Mark

Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes

酰化偶联亲脂性极化诱导(Acyl-cLIP):一种用于脂质转移酶和水解酶的通用检测方法

Lanyon-Hogg, Thomas; Ritzefeld, Markus; Sefer, Lea; Bickel, Jasmine K; Rudolf, Amalie F; Panyain, Nattawadee; Bineva-Todd, Ganka; Ocasio, Cory A; O'Reilly, Nicola; Siebold, Christian; Magee, Anthony I; Tate, Edward W

Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A

使用 Sortase A 对 N-肉豆蔻酰转移酶活性和抑制进行全蛋白质组分析

Andrea Goya Grocin, Remigiusz A Serwa, Julia Morales Sanfrutos, Markus Ritzefeld, Edward W Tate

Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain

蝙蝠 IFITM3 限制依赖于 S-棕榈酰化和 CD225 结构域内的多态性位点

Camilla To Benfield, Farrell MacKenzie, Markus Ritzefeld, Michela Mazzon, Stuart Weston, Edward W Tate, Boon Han Teo, Sarah E Smith, Paul Kellam, Edward C Holmes, Mark Marsh

Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation

微流控迁移率变化检测法用于实时分析肽N-棕榈酰化

Lanyon-Hogg, Thomas; Patel, Neki V; Ritzefeld, Markus; Boxall, Katherine J; Burke, Rosemary; Blagg, Julian; Magee, Anthony I; Tate, Edward W

Characterization of Hedgehog Acyltransferase Inhibitors Identifies a Small Molecule Probe for Hedgehog Signaling by Cancer Cells

对 Hedgehog 酰基转移酶抑制剂的特性分析鉴定出一种用于癌细胞 Hedgehog 信号通路的小分子探针

Rodgers, Ursula R; Lanyon-Hogg, Thomas; Masumoto, Naoko; Ritzefeld, Markus; Burke, Rosemary; Blagg, Julian; Magee, Anthony I; Tate, Edward W

Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells

壳聚糖-microRNA 纳米复合物向 MCF-7 乳腺癌细胞传递基因的物理化学和生物学表征

B Santos-Carballal, L J Aaldering, M Ritzefeld, S Pereira, N Sewald, B M Moerschbacher, M Götte, F M Goycoolea