日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

应力颗粒内部TDP-43的凝聚相分离会生成病理聚集体。

Xiao Yan ,David Kuster ,Priyesh Mohanty ,Jik Nijssen ,Karina Pombo-García ,Jorge Garcia Morato ,Azamat Rizuan ,Titus M Franzmann ,Aleksandra Sergeeva ,Anh M Ly ,Feilin Liu ,Patricia M Passos ,Leah George ,Szu-Huan Wang ,Jayakrishna Shenoy ,Helen L Danielson ,Busra Ozguney ,Alf Honigmann ,Yuna M Ayala ,Nicolas L Fawzi ,Dennis W Dickson ,Wilfried Rossoll ,Jeetain Mittal ,Simon Alberti ,Anthony A Hyman

Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain

TDP-43 C端结构域保守区螺旋介导多聚化的结构细节

Rizuan, Azamat; Shenoy, Jayakrishna; Mohanty, Priyesh; Dos Passos, Patricia M; Mercado Ortiz, José F; Bai, Leanna; Viswanathan, Renjith; Zaborowksy, Julia; Wang, Szu-Huan; Johnson, Victoria; Mamede, Lohany D; Titus, Amanda R; Ayala, Yuna M; Ghirlando, Rodolfo; Mittal, Jeetain; Fawzi, Nicolas L

Multiscale Simulations Elucidate the Mechanism of Polyglutamine Aggregation and the Role of Flanking Domains in Fibril Polymorphism

多尺度模拟阐明了聚谷氨酰胺聚集的机制以及侧翼结构域在原纤维多态性中的作用

Kulshrestha, Avijeet; Phan, Tien Minh; Rizuan, Azamat; Mohanty, Priyesh; Mittal, Jeetain

Exploring the Effectiveness of Chlorophacinone in Managing Urban Rat Infestation: A Laboratory Study on the Norway Rat, Rattus norvegicus, a Common Urban Rat in Malaysia

氯鼠酮防治城市鼠患的有效性研究:以马来西亚常见城市鼠种——褐家鼠(Rattus norvegicus)为例的实验室研究

Mohd-Noh, Ariff Ateed; Rashid, Yusdayati; Muhammad-Nasir, Dzulhelmi; Zainal-Abidin, Cik Mohd Rizuan

Multiscale simulations elucidate the mechanism of polyglutamine aggregation and the role of flanking domains in fibril polymorphism

多尺度模拟阐明了聚谷氨酰胺聚集的机制以及侧翼结构域在原纤维多态性中的作用

Kulshrestha, Avijeet; Phan, Tien Minh; Rizuan, Azamat; Mohanty, Priyesh; Mittal, Jeetain

Expanding the molecular language of protein liquid-liquid phase separation

扩展蛋白质液-液相分离的分子语言

Rekhi, Shiv; Garcia, Cristobal Garcia; Barai, Mayur; Rizuan, Azamat; Schuster, Benjamin S; Kiick, Kristi L; Mittal, Jeetain

A complex network of interdomain interactions underlies the conformational ensemble of monomeric TDP-43 and modulates its phase behavior

单体TDP-43的构象集合由复杂的结构域间相互作用网络构成,并调节其相行为。

Mohanty, Priyesh; Rizuan, Azamat; Kim, Young C; Fawzi, Nicolas L; Mittal, Jeetain

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

应力颗粒内部TDP-43的凝聚相分离会生成病理聚集体。

Yan, Xiao; Kuster, David; Mohanty, Priyesh; Nijssen, Jik; Pombo-García, Karina; Rizuan, Azamat; Franzmann, Titus M; Sergeeva, Aleksandra; Passos, Patricia M; George, Leah; Wang, Szu-Huan; Shenoy, Jayakrishna; Danielson, Helen L; Honigmann, Alf; Ayala, Yuna M; Fawzi, Nicolas L; Mittal, Jeetain; Alberti, Simon; Hyman, Anthony A

Structural details of helix-mediated TDP-43 C-terminal domain multimerization

螺旋介导的 TDP-43 C 端结构域多聚化的结构细节

Azamat Rizuan, Jayakrishna Shenoy, Priyesh Mohanty, Patricia M S Dos Passos, José F Mercado Ortiz, Leanna Bai, Renjith Viswanathan, Szu-Huan Wang, Victoria Johnson, Lohany D Mamede, Yuna M Ayala, Rodolfo Ghirlando, Jeetain Mittal, Nicolas L Fawzi

A Zn-dependent structural transition of SOD1 modulates its ability to undergo phase separation

SOD1 的 Zn 依赖性结构转变调节其进行相分离的能力

Bidisha Das #, Sumangal Roychowdhury #, Priyesh Mohanty, Azamat Rizuan, Joy Chakraborty, Jeetain Mittal, Krishnananda Chattopadhyay