日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes

CFAP20 可阻止 RNAPII 进入同向复制体的路径

Uruci, Sidrit; Boer, Daphne E C; Chrystal, Paul W; Lalonde, Maxime; Panagopoulos, Andreas; Yakoub, George; Kirdök, Idil; de Lint, Klaas; van der Woude, Melanie; Wendel, Tiemen J; Brussee, Sem J; Wondergem, Annelotte P; van Overbeek, Nila K; Schotman, Nini; Lingeman, Jolanthe; Ljungman, Mats; van Oudenaarden, Alexander; van Attikum, Haico; Vertegaal, Alfred C O; Noordermeer, Sylvie M; Wolthuis, Rob M F; Altmeyer, Matthias; Hamperl, Stephan; Tropepe, Vincent; van den Berg, Jeroen; van den Heuvel, Diana; Luijsterburg, Martijn S

An unexpected role of CLASP1 in radiation response and S-phase regulation of head and neck cancer cells

CLASP1在头颈癌细胞的放射反应和S期调控中发挥意想不到的作用

de Roest, Reinout H; Buijze, Marijke; Veth, Myrthe; de Lint, Klaas; Pai, Govind; Rooimans, Martin A; Wolthuis, Rob M F; Brink, Arjen; Poell, Jos B; Brakenhoff, Ruud H

Protocol for high-precision CRISPR-Cas12a-based SNV detection on synthetic DNA, cell line cfDNA models, and liquid biopsies

用于合成DNA、细胞系cfDNA模型和液体活检的高精度CRISPR-Cas12a基SNV检测方案

Kavish A V Kohabir ,Jasper Linthorst ,Rob M F Wolthuis ,Erik A Sistermans

STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

STK19促进转录偶联DNA修复过程中受损停滞的RNAPII的清除

Diana van den Heuvel,Marta Rodríguez-Martínez,Paula J van der Meer,Nicolas Nieto Moreno,Jiyoung Park,Hyun-Suk Kim,Janne J M van Schie,Annelotte P Wondergem,Areetha D'Souza,George Yakoub,Anna E Herlihy,Krushanka Kashyap,Thierry Boissière,Jane Walker,Richard Mitter,Katja Apelt,Klaas de Lint,Idil Kirdök,Mats Ljungman,Rob M F Wolthuis,Patrick Cramer,Orlando D Schärer,Goran Kokic,Jesper Q Svejstrup,Martijn S Luijsterburg

Synthetic mismatches enable specific CRISPR-Cas12a-based detection of genome-wide SNVs tracked by ARTEMIS

合成错配能够实现基于 CRISPR-Cas12a 的特异性检测,从而追踪 ARTEMIS 所追踪的全基因组 SNV。

Kavish A V Kohabir ,Jasper Linthorst ,Lars O Nooi ,Rick Brouwer ,Rob M F Wolthuis ,Erik A Sistermans

CRISPR screens in sister chromatid cohesion defective cells reveal PAXIP1-PAGR1 as regulator of chromatin association of cohesin

在姐妹染色单体黏附缺陷细胞中进行的 CRISPR 筛选表明 PAXIP1-PAGR1 是黏附蛋白染色质结合的调节剂

Janne J M van Schie, Klaas de Lint, Thom M Molenaar, Macarena Moronta Gines, Jesper A Balk, Martin A Rooimans, Khashayar Roohollahi, Govind M Pai, Lauri Borghuis, Anisha R Ramadhin, Francesco Corazza, Josephine C Dorsman, Kerstin S Wendt, Rob M F Wolthuis, Job de Lange

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma

全基因组siRNA筛选发现RBBP9功能可能是范可尼贫血缺陷型头颈部鳞状细胞癌的潜在靶点

Govind Pai ,Khashayar Roohollahi ,Davy Rockx ,Yvonne de Jong ,Chantal Stoepker ,Charlotte Pennings ,Martin Rooimans ,Lianne Vriend ,Sander Piersma ,Connie R Jimenez ,Renee X De Menezes ,Victor W Van Beusechem ,Ruud H Brakenhoff ,Hein Te Riele ,Rob M F Wolthuis ,Josephine C Dorsman

Isocaloric Substitution of Plant-Based Protein for Animal-Based Protein and Cardiometabolic Risk Factors in a Multiethnic Asian Population

在多民族亚洲人群中,以等热量植物蛋白替代动物蛋白对心血管代谢风险因素的影响

Lee, Yu Qi; Chia, Airu; Whitton, Clare; Cameron-Smith, David; Sim, Xueling; van Dam, Rob M; F-F Chong, Mary

In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region

基于 CRISPR-Cas12a 的体外检测 crRNA 种子区域以外的癌症相关 TP53 热点突变

Kavish A V Kohabir, Lars O Nooi, Arjen Brink, Ruud H Brakenhoff, Erik A Sistermans, Rob M F Wolthuis

ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data

ShrinkCRISPR:一种用于CRISPR-Cas9筛选数据差异适应度分析的灵活方法

Tissier, Renaud L M; Schie, Janne J M van; Wolthuis, Rob M F; Lange, Job de; Menezes, Renée de