日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-activity relationships of thiadiazole agonists of the human secretin receptor

人类促胰液素受体噻二唑激动剂的构效关系

Robert Ardecky, Daniela G Dengler, Kaleeckal G Harikumar, Mathew M Abelman, Jiwen Zou, Bryan A Kramer, Santhi Reddy Ganji, Steve Olson, Alina Ly, Nikhil Puvvula, Chen-Ting Ma, Raghuveer Ramachandra, Eduard A Sergienko, Laurence J Miller

Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells

发现针对白血病细胞中致癌酪氨酸磷酸酶 SHP2 的新型呋喃苯甲酰胺抑制剂

Dhanya Raveendra-Panickar, Darren Finlay, Fabiana Izidro Layng, Lester J Lambert, Maria Celeridad, Ming Zhao, Karina Barbosa, Laurent J S De Backer, Elizabeth Kwong, Palak Gosalia, Socorro Rodiles, John Holleran, Robert Ardecky, Stefan Grotegut, Steven Olson, John H Hutchinson, Elena B Pasquale, Kri

Discovery of small molecule positive allosteric modulators of the secretin receptor

发现促胰液素受体的小分子正变构调节剂

Daniela G Dengler, Kaleeckal G Harikumar, Sirkku Pollari, Qing Sun, Brock T Brown, Aki Shinoki-Iwaya, Robert Ardecky, Laurence J Miller, Eduard A Sergienko

Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin Receptors

开发用于鉴定针对促胰液素受体的小分子调节剂的测试漏斗

Daniela G Dengler, Qing Sun, John Holleran, Sirkku Pollari, Jannis Beutel, Brock T Brown, Aki Shinoki Iwaya, Robert Ardecky, Kaleeckal G Harikumar, Laurence J Miller, Eduard A Sergienko

Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines

苯二氮卓酮衍生物可防止人类神经元细胞系中内质网应激介导的细胞死亡

Haixia Zou, Allison S Limpert, Jiwen Zou, Anna Dembo, Pooi-San Lee, Daniel Grant, Robert Ardecky, Anthony B Pinkerton, Gavin K Magnuson, Mark E Goldman, Juan Rong, Peter Teriete, Douglas J Sheffler, John C Reed, Nicholas D P Cosford