日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

G1T48(一种口服选择性雌激素受体降解剂)和 CDK4/6 抑制剂 lerociclib 可抑制内分泌抗性乳腺癌动物模型中的肿瘤生长

Kaitlyn J Andreano, Suzanne E Wardell, Jennifer G Baker, Taylor K Desautels, Robert Baldi, Christina A Chao, Kendall A Heetderks, Yeeun Bae, Rui Xiong, Debra A Tonetti, Lauren M Gutgesell, Jiong Zhao, Jessica A Sorrentino, Delita A Thompson, John E Bisi, Jay C Strum, Gregory R J Thatcher, John D Nor

The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

谱系决定因子GRHL2与FOXA1协同作用,在内分泌治疗耐药性乳腺癌中建立可靶向通路

Kimberly J Cocce ,Jeff S Jasper ,Taylor K Desautels ,Logan Everett ,Suzanne Wardell ,Thomas Westerling ,Robert Baldi ,Tricia M Wright ,Kendall Tavares ,Alex Yllanes ,Yeeun Bae ,Jeremy T Blitzer ,Craig Logsdon ,Daniel P Rakiec ,David A Ruddy ,Tiancong Jiang ,Gloria Broadwater ,Terry Hyslop ,Allison Hall ,Muriel Laine ,Linda Phung ,Geoffrey L Greene ,Lesley-Ann Martin ,Sunil Pancholi ,Mitch Dowsett ,Simone Detre ,Jeffrey R Marks ,Gregory E Crawford ,Myles Brown ,John D Norris ,Ching-Yi Chang ,Donald P McDonnell

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer

ERRα 抑制可阻止线粒体丙酮酸吸收,从而暴露 NADPH 生成途径作为乳腺癌中可靶向的弱点

Sunghee Park, Rachid Safi, Xiaojing Liu, Robert Baldi, Wen Liu, Juan Liu, Jason W Locasale, Ching-Yi Chang, Donald P McDonnell

A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product

利用天然产物抑制GAPDH选择性靶向Warburg效应的预测模型

Maria V Liberti ,Ziwei Dai ,Suzanne E Wardell ,Joshua A Baccile ,Xiaojing Liu ,Xia Gao ,Robert Baldi ,Mahya Mehrmohamadi ,Marc O Johnson ,Neel S Madhukar ,Alexander A Shestov ,Iok I Christine Chio ,Olivier Elemento ,Jeffrey C Rathmell ,Frank C Schroeder ,Donald P McDonnell ,Jason W Locasale