日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice

使用甘尼妥单抗阻断 IGF1R 会对小鼠的 GH-IGF 轴产生全身影响

Gordon Moody, Pedro J Beltran, Petia Mitchell, Elaina Cajulis, Young-Ah Chung, David Hwang, Richard Kendall, Robert Radinsky, Pinchas Cohen, Frank J Calzone

Epitope-specific mechanisms of IGF1R inhibition by ganitumab

加尼单抗抑制 IGF1R 的表位特异性机制

Frank J Calzone, Elaina Cajulis, Young-Ah Chung, Mei-Mei Tsai, Petia Mitchell, John Lu, Ching Chen, Jilin Sun, Robert Radinsky, Richard Kendall, Pedro J Beltran

Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models

ganitumab (AMG 479) 单独使用和与雷帕霉素联合使用对尤文氏肉瘤和成骨肉瘤模型的疗效

Pedro J Beltran, Young-Ah Chung, Gordon Moody, Petia Mitchell, Elaina Cajulis, Steven Vonderfecht, Richard Kendall, Robert Radinsky, Frank J Calzone

Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth

选择性强效 Raf 抑制剂反而刺激正常细胞增殖和肿瘤生长

Josette Carnahan, Pedro J Beltran, Carol Babij, Quynh Le, Mark J Rose, Steven Vonderfecht, Joseph L Kim, Adrian L Smith, Karthik Nagapudi, Martin A Broome, Manory Fernando, Hue Kha, Brian Belmontes, Robert Radinsky, Richard Kendall, Teresa L Burgess

Soluble c-Met receptors inhibit phosphorylation of c-Met and growth of hepatocyte growth factor: c-Met-dependent tumors in animal models

可溶性 c-Met 受体抑制 c-Met 磷酸化和肝细胞生长因子的生长:动物模型中的 c-Met 依赖性肿瘤

Angela Coxon, Karen Rex, Susanne Meyer, Jianling Sun, Jilin Sun, Qing Chen, Robert Radinsky, Richard Kendall, Teresa L Burgess

AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells

AMG 479 是一种全人抗胰岛素样生长因子受体 I 型单克隆抗体,可抑制胰腺癌细胞的生长和存活

Pedro J Beltran, Petia Mitchell, Young-A Chung, Elaina Cajulis, John Lu, Brian Belmontes, Joanne Ho, Mei Mei Tsai, Min Zhu, Steven Vonderfecht, Renato Baserga, Richard Kendall, Robert Radinsky, Frank J Calzone

Effects of palifermin on antitumor activity of chemotherapeutic and biological agents in human head and neck and colorectal carcinoma xenograft models

帕利夫明对人类头颈部和结肠直肠癌异种移植模型中化疗和生物制剂抗肿瘤活性的影响

Rachael Brake, Charlie Starnes, John Lu, Danlin Chen, Suijin Yang, Robert Radinsky, Luis Borges