M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss
M1毒蕈碱受体变构调节剂可减缓朊病毒引起的神经退行性变并恢复记忆丧失
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI87526
Bradley, Sophie J; Bourgognon, Julie-Myrtille; Sanger, Helen E; Verity, Nicholas; Mogg, Adrian J; White, David J; Butcher, Adrian J; Moreno, Julie A; Molloy, Colin; Macedo-Hatch, Timothy; Edwards, Jennifer M; Wess, Jurgen; Pawlak, Robert; Read, David J; Sexton, Patrick M; Broad, Lisa M; Steinert, Joern R; Mallucci, Giovanna R; Christopoulos, Arthur; Felder, Christian C; Tobin, Andrew B