日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted BDNF upregulation via upstream open reading frame disruption

通过上游开放阅读框破坏靶向上调BDNF

Feng, Ning; Goedert, Thomas; Svrzikapa, Nenad; Yan, Dongnan; Friedrichsen, Hans J; Hanson, Britt; Ljungdahl, Alicia; Dafinca, Ruxandra; Talbot, Kevin; Sanders, Stephan J; Gupta, Dhanu; Wood, Mathew J A; Roberts, Thomas C

Myonuclear Domain-Associated and Central Nucleation-Dependent Spatial Restriction of Dystrophin Protein Expression

肌核结构域相关和中心核依赖的肌营养不良蛋白表达的空间限制

Chwalenia, Katarzyna; Feng, Vivi-Yun; Hemmer, Nicole; Hildyard, John C W; Roskrow, Liberty E; Piercy, Richard J; Wang, Eric T; Aartsma-Rus, Annemieke; van Putten, Maaike; Wood, Matthew J A; Roberts, Thomas C

Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors.

改造细胞外囊泡,以实现包括基因组编辑器在内的多模式治疗药物的高效细胞内递送

Liang Xiuming, Gupta Dhanu, Xie Junhua, Van Wonterghem Elien, Van Hoecke Lien, Hean Justin, Niu Zheyu, Ghaeidamini Marziyeh, Wiklander Oscar P B, Zheng Wenyi, Wiklander Rim Jawad, He Rui, Mamand Doste R, Bost Jeremy, Zhou Guannan, Zhou Houze, Roudi Samantha, Estupiñán H Yesid, Rädler Julia, Zickler Antje M, Görgens André, Hou Vicky W Q, Slovak Radka, Hagey Daniel W, de Jong Olivier G, Uy Aileen Geobee, Zong Yuanyuan, Mäger Imre, Perez Carla Martin, Roberts Thomas C, Carter Dave, Vader Pieter, Esbjörner Elin K, de Fougerolles Antonin, Wood Matthew J A, Vandenbroucke Roosmarijn E, Nordin Joel Z, El Andaloussi Samir

AAV microdystrophin gene replacement therapy for Duchenne muscular dystrophy: progress and prospects

AAV微型肌营养不良蛋白基因替代疗法治疗杜氏肌营养不良症:进展与展望

Chwalenia, Katarzyna; Feng, Vivi-Yun; Hemmer, Nicole; Friedrichsen, Hans J; Vorobieva, Ioulia; Wood, Matthew J A; Roberts, Thomas C

Progress and prospects in antisense oligonucleotide-mediated exon skipping therapies for Duchenne muscular dystrophy

反义寡核苷酸介导的杜氏肌营养不良症外显子跳跃疗法的进展与前景

Chwalenia, Katarzyna; Wood, Matthew J A; Roberts, Thomas C

An extracellular vesicle delivery platform based on the PTTG1IP protein

基于PTTG1IP蛋白的细胞外囊泡递送平台

Martin Perez, Carla; Liang, Xiuming; Gupta, Dhanu; Haughton, Emily R; Conceição, Mariana; Mäger, Imre; El Andaloussi, Samir; Wood, Matthew J A; Roberts, Thomas C

Long-term dystrophin restoration supports development of splice correction therapy for DMD patients with exon 2 duplications

长期肌营养不良蛋白恢复支持针对外显子2重复的DMD患者的剪接校正疗法的发展

Roberts, Thomas C

Investigating Eukaryotic Elongation Factor 2 Kinase/Eukaryotic Translation Elongation Factor 2 Pathway Regulation and Its Role in Protein Synthesis Impairment during Disuse-Induced Skeletal Muscle Atrophy.

研究真核延伸因子 2Â 激酶/真核翻译延伸因子 2 通路调控及其在废用性骨骼肌萎缩引起的蛋白质合成障碍中的作用

Vilchinskaya Natalia, Lim Wooi Fang, Belova Svetlana, Roberts Thomas C, Wood Matthew J A, Lomonosova Yulia

Nanoscale photobiotinylation, pulldown and sequencing of region-specific DNA from intact cells

利用纳米级光生物素化、下拉和测序技术,从完整细胞中提取特定区域的DNA

Roberts, Thomas C; Kushner, Max; Crowley, Jack C; Ozer, Abdullah; Wang, Juan; Ray, Judhajeet; Lis, John T; Zipfel, Warren R

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD

在DMD的肌营养不良蛋白/肌营养蛋白双敲除小鼠模型中,CRISPR介导的外显子切除后肌营养不良蛋白的重新表达不均匀。

Hanson, Britt; Stenler, Sofia; Ahlskog, Nina; Chwalenia, Katarzyna; Svrzikapa, Nenad; Coenen-Stass, Anna M L; Weinberg, Marc S; Wood, Matthew J A; Roberts, Thomas C