Roberts Thomas M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

PTEN Loss Promotes PI3KÎ² Phosphorylation and EPHA2/SRC/p-PI3KÎ²Y962 Complex Assembly to Drive Tumorigenesis.

PTEN 缺失促进 PI3Kβ 磷酸化和 EPHA2/SRC/p-PI3KβY962 复合物组装，从而驱动肿瘤发生。

期刊:Cancer Discovery

影响因子:33.3

doi:10.1158/2159-8290.CD-25-1126

Tang Shuang, Zhou Qian, Bergholz Johann S, Jiang Tao, Wang Weihua, Ji Renlei, Huang Wendi, Wu Jiachen, Li Yutong, Wan Xiaochun, He Xiadi, Jing Qianchen, Sun Menghong, Johnson Jared L, Yaron-Barir Tomer M, Li Da-Qiang, Dai Bo, Wang Zefeng, Li Xiaoling, Cantley Lewis C, Roberts Thomas M, Zhao Jean J

发表日期：2026

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Spermidine reduces peri-implant inflammation and fibrosis to nurture osseointegration

亚精胺可减轻种植体周围的炎症和纤维化，从而促进骨整合。

期刊:Bioactive Materials

影响因子:20.3

doi:10.1016/j.bioactmat.2025.09.036

Liu, Qiming; Wu, Qianqian; Cao, Tingting; Miao, Rundong; Wang, Chenyu; Zhang, Jiawei; Gao, Xue; Wang, Li; Shi, Guoxin; Lai, Jinyu; Yang, Runjiao; Piao, Xianshu; Yu, Jiaao; Wang, Jincheng; Liang, Song; Kou, Shuqing; Roberts, Thomas M; Wang, Bingdi; Liu, Zhenning

发表日期：2026

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Statin-dye conjugates for selective targeting of KRAS mutant cancer cells

用于选择性靶向KRAS突变癌细胞的他汀类药物-染料偶联物

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0340189

Moon, Hye-Ran; Cai, Zhenying; Cho, Bo Kyung; Chang, Hyeyoun; Hong, Seung Taek; Zhao, Jean J; Kwon, Ick Chan; Roberts, Thomas M; Han, Bumsoo; Ryu, Ju Hee

细胞生物学

发表日期：2026

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ERK-dependent protein phosphorylation in KRAS-mutant cancer: a mix of the expected and surprising

KRAS突变癌症中ERK依赖性蛋白磷酸化：预期与意外的交织

期刊:Trends in Biochemical Sciences

影响因子:11

doi:10.1016/j.tibs.2024.10.011

Huang, Kevin; Wang, Yubao; Roberts, Thomas M

发表日期：2025

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A degradable form of polyoma small T antigen reveals the high specificity of TAZ in regulating gene expression.

多瘤病毒小T抗原的可降解形式揭示了TAZ在调节基因表达方面的高度特异性

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2426862122

Wang Yubao, Manokaran Cherubin, Huang Kevin, Schaffhausen Brian, Roberts Thomas M

发表日期：2025

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Statin-dye conjugates for selective targeting of KRAS mutant cancer cells

用于选择性靶向KRAS突变癌细胞的他汀类药物-染料偶联物

doi:10.1101/2025.06.03.657329

Moon, Hye-Ran; Cai, Zhenying; Cho, Bo Kyung; Chang, Hyeyoun; Hong, Seung Taek; Zhao, Jean J; Kwon, Ick Chan; Roberts, Thomas M; Han, Bumsoo; Ryu, Ju Hee

细胞生物学

发表日期：2025

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Loss of the tumor suppressor PTEN activates cell-intrinsic interferon signaling to drive immune resistance.

肿瘤抑制因子 PTEN 的缺失会激活细胞内在的干扰素信号传导，从而导致免疫抵抗。

doi:10.1101/2025.09.17.676669

Wang Yubao, Manokaran Cherubin, Chen Jiajia, Gu Hao, Liu David, Bousso Philippe, Zhao Jean J, Roberts Thomas M

细胞生物学

免疫/内分泌

发表日期：2025

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Dual Modes of Gene Regulation by CDK12.

CDK12 的双重基因调控模式。

doi:10.1101/2025.09.22.677923

Wang Yubao, Baluapuri Apoorva, Manokaran Cherubin, Ni Jing, Jiang Tao, Janssens Roel C, Marteijn Jurgen A, Adelman Karen, Zhao Jean, Roberts Thomas M

发表日期：2025

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PI3Kγ maintains the self-renewal of acute myeloid leukemia stem cells by regulating the pentose phosphate pathway

PI3Kγ通过调控磷酸戊糖途径维持急性髓系白血病干细胞的自我更新能力。

影响因子:23.1

doi:10.1182/blood.2023022202

Gu, Hao; Chen, Chiqi; Hou, Zhi-Shuai; He, Xia-Di; Xie, Shaozhen; Ni, Jing; Qian, Changli; Cheng, Xin; Jiang, Tao; Yang, Ce; Roberts, Thomas M; Zheng, Junke; Varner, Judith A; Armstrong, Scott A; Zhao, Jean J

发育与干细胞

细胞生物学

发表日期：2024

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Spermidine-Functionalized Injectable Hydrogel Reduces Inflammation and Enhances Healing of Acute and Diabetic Wounds In Situ

亚精胺功能化注射水凝胶可减轻炎症并促进急性及糖尿病伤口原位愈合

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202310162

Wu, Qianqian; Yang, Runjiao; Fan, Wenxuan; Wang, Li; Zhan, Jing; Cao, Tingting; Liu, Qiming; Piao, Xianshu; Zhong, Yinghui; Zhao, Wenxian; Zhang, Shuhan; Yu, Jiaao; Liang, Song; Roberts, Thomas M; Wang, Bingdi; Liu, Zhenning

Immunology/Inflammation

发表日期：2024

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