日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

On the Discorhabdins Leading to the Aleutianamine Ring System: A One-Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology

关于Discorhabdins通往Aleutianamine环系的转化:通过计算和实验研究表征的一步原位转化及其对生物合成、合成和药理学的影响

Dickinson, Cody F; Potluri, Abhay; Bland, Alison M; Flipse, Samuel M; Hanna, George S; Wagner, Ryan T; Robertson, Keith D; Ho, Thai H; Sprague, Daniel J; Hoff, Gerald R; Stone, Robert P; Tius, Marcus A; Tantillo, Dean J; Hamann, Mark T

Epigenetic heterogeneity hotspots in human liver disease progression

人类肝病进展中的表观遗传异质性热点

Hlady, Ryan A; Zhao, Xia; El Khoury, Louis Y; Wagner, Ryan T; Luna, Aesis; Pham, Kien; Pyrosopoulos, Nikolaos T; Jain, Dhanpat; Wang, Liguo; Liu, Chen; Robertson, Keith D

SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation.

SETD2 功能丧失使细胞对 NSD1 指导的 H3K36 甲基化的表观遗传靶向作用变得异常敏感

Wagner Ryan T, Hlady Ryan A, Pan Xiaoyu, Wang Liguo, Kim Sungho, Zhao Xia, El Khoury Louis Y, Shaikh Shafiq, Zhong Jian, Lee Jeong-Heon, Grembecka Jolanta, Cierpicki Tomasz, Ho Thai H, Robertson Keith D

Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response

单细胞多组学揭示了DNMT3A和TET2突变克隆性造血在炎症反应中的不同作用

Mohammed Ismail, Wazim; Fernandez, Jenna A; Binder, Moritz; Lasho, Terra L; Kim, Minsuk; Geyer, Susan M; Mazzone, Amelia; Finke, Christy M; Mangaonkar, Abhishek A; Lee, Jeong-Heon; Wang, Liguo; Kim, Kwan Hyun; Simon, Vernadette A; Rakhshan Rohakthar, Fariborz; Munankarmy, Amik; Byeon, Seul Kee; Schwager, Susan M; Harrington, Jonathan J; Snyder, Melissa R; Robertson, Keith D; Pandey, Akhilesh; Wieben, Eric D; Chia, Nicholas; Gaspar-Maia, Alexandre; Patnaik, Mrinal M

Exploring Glypican-3 targeted CAR-NK treatment and potential therapy resistance in hepatocellular carcinoma

探索以 Glypican-3 为靶点的 CAR-NK 疗法在肝细胞癌中的作用及其潜在的耐药性

Yang, Lei; Pham, Kien; Xi, Yibo; Wu, Qunfeng; Liu, Dongfang; Robertson, Keith D; Liu, Chen

Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome

透明细胞肾细胞癌中广泛的肿瘤内区域表观遗传异质性靶向肾脏增强子,并与不良预后相关。

El Khoury, Louis Y; Pan, Xiaoyu; Hlady, Ryan A; Wagner, Ryan T; Shaikh, Shafiq; Wang, Liguo; Humphreys, Mitchell R; Castle, Erik P; Stanton, Melissa L; Ho, Thai H; Robertson, Keith D

Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancer

鉴定与低风险分期、大小、分级和坏死(SSIGN)评分透明细胞肾细胞癌不良预后相关的DNA甲基化特征

El Khoury, Louis Y; Fu, Shuang; Hlady, Ryan A; Wagner, Ryan T; Wang, Liguo; Eckel-Passow, Jeanette E; Castle, Erik P; Stanton, Melissa L; Thompson, R Houston; Parker, Alexander S; Ho, Thai H; Robertson, Keith D

Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling

快速循环型和非快速循环型双相情感障碍患者的血浆游离DNA甲基化组学研究

Ho, Ada Man-Choi; Winham, Stacey J; McCauley, Bryan M; Kundakovic, Marija; Robertson, Keith D; Sun, Zhifu; Ordog, Tamas; Webb, Lauren M; Frye, Mark A; Veldic, Marin

Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays

利用Illumina MethylationEPIC BeadChip微阵列区分主动和被动DNA去甲基化

Tiedemann, Rochelle L; Eden, Hope E; Huang, Zhijun; Robertson, Keith D; Rothbart, Scott B

Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

在循环游离DNA中,基于DNA甲基化的肝细胞癌诊断生物标志物的全基因组发现与验证

Hlady, Ryan A; Zhao, Xia; Pan, Xiaoyu; Yang, Ju Dong; Ahmed, Fowsiyo; Antwi, Samuel O; Giama, Nasra H; Patel, Tushar; Roberts, Lewis R; Liu, Chen; Robertson, Keith D