日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Endothermic physiology of extinct megatooth sharks

已灭绝巨齿鲨的恒温生理

Griffiths, Michael L; Eagle, Robert A; Kim, Sora L; Flores, Randon J; Becker, Martin A; Maisch, Harry M 4th; Trayler, Robin B; Chan, Rachel L; McCormack, Jeremy; Akhtar, Alliya A; Tripati, Aradhna K; Shimada, Kenshu

Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis

STARD4 的稳定减少会改变胆固醇调节和脂质稳态

David B Iaea, Zachary R Spahr, Rajesh K Singh, Robin B Chan, Bowen Zhou, Rohan Bareja, Olivier Elemento, Gilbert Di Paolo, Xiaoxue Zhang, Frederick R Maxfield

Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures

神经元溶酶体功能障碍会释放含有APP C端片段和独特脂质特征的外泌体。

André M Miranda ,Zofia M Lasiecka ,Yimeng Xu ,Jessi Neufeld ,Sanjid Shahriar ,Sabrina Simoes ,Robin B Chan ,Tiago Gil Oliveira ,Scott A Small ,Gilbert Di Paolo

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation

内质网-质膜接触位点整合甾醇和磷脂调节

Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Jeremy S Dittman, William J Rice, Robin B Chan, Gilbert Di Paolo, Christopher T Beh, Anant K Menon

Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease

APP-C99 在线粒体相关内质网膜上的定位增加导致阿尔茨海默病中的线粒体功能障碍

Marta Pera, Delfina Larrea, Cristina Guardia-Laguarta, Jorge Montesinos, Kevin R Velasco, Rishi R Agrawal, Yimeng Xu, Robin B Chan, Gilbert Di Paolo, Mark F Mehler, Geoffrey S Perumal, Frank P Macaluso, Zachary Z Freyberg, Rebeca Acin-Perez, Jose Antonio Enriquez, Eric A Schon, Estela Area-Gomez

Cyp8b1 ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption

CYP8B1 消融可防止西方饮食引起的体重增加和因脂肪吸收受损而导致的肝脂肪变性

Enrico Bertaggia, Kristian K Jensen, Jose Castro-Perez, Yimeng Xu, Gilbert Di Paolo, Robin B Chan, Liangsu Wang, Rebecca A Haeusler

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis

TTC39B 缺乏可稳定 LXR,从而减少动脉粥样硬化和脂肪性肝炎

Joanne Hsieh, Masahiro Koseki, Matthew M Molusky, Emi Yakushiji, Ikuyo Ichi, Marit Westerterp, Jahangir Iqbal, Robin B Chan, Sandra Abramowicz, Liana Tascau, Shunichi Takiguchi, Shizuya Yamashita, Carrie L Welch, Gilbert Di Paolo, M Mahmood Hussain, Jay H Lefkowitch, Daniel J Rader, Alan R Tall

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

HS1BP3 通过调节磷脂酸水平来负向调节自噬

Petter Holland, Helene Knævelsrud, Kristiane Søreng, Benan J Mathai, Alf Håkon Lystad, Serhiy Pankiv, Gunnveig T Bjørndal, Sebastian W Schultz, Viola H Lobert, Robin B Chan, Bowen Zhou, Knut Liestøl, Sven R Carlsson, Thomas J Melia, Gilbert Di Paolo, Anne Simonsen

Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms

行为特征通过分离的迭代体细胞和配子表观遗传机制跨代传播

Emma Mitchell, Shifra L Klein, Kimon V Argyropoulos, Ali Sharma, Robin B Chan, Judit Gal Toth, Luendreo Barboza, Charlotte Bavley, Analia Bortolozzi, Qiuying Chen, Bingfang Liu, Joanne Ingenito, Willie Mark, Jarrod Dudakov, Steven Gross, Gilbert Di Paolo, Francesc Artigas, Marcel van den Brink, Mikl

Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis

抑制载脂蛋白 B 合成可刺激内质网自噬,从而预防脂肪变性

Donna M Conlon, Tiffany Thomas, Tatyana Fedotova, Antonio Hernandez-Ono, Gilbert Di Paolo, Robin B Chan, Kelly Ruggles, Sarah Gibeley, Jing Liu, Henry N Ginsberg