A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy
与间质性肺病相关的非 BRICHOS SFTPC 突变体 (SP-CI73T) 会促进巨自噬的晚期阻断,从而破坏细胞蛋白质稳态和线粒体自噬
期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology
影响因子:3.6
doi:10.1152/ajplung.00217.2014
Arie Hawkins, Susan H Guttentag, Robin Deterding, William K Funkhouser, Jennifer L Goralski, Shampa Chatterjee, Surafel Mulugeta, Michael F Beers