日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies

在人呼吸道基底细胞中进行的化合物筛选发现,Wnt通路激活剂具有潜在的促再生治疗作用。

Yuki Ishii ,Jessica C Orr ,Marie-Belle El Mdawar ,Denise R Bairros de Pilger ,David R Pearce ,Kyren A Lazarus ,Rebecca E Graham ,Marko Z Nikolić ,Robin Ketteler ,Neil O Carragher ,Sam M Janes ,Robert E Hynds

Automated high-content imaging in iPSC-derived neuronal progenitors

iPSC 衍生的神经元祖细胞的自动高内涵成像

Apostolos Papandreou, Christin Luft, Serena Barral, Janos Kriston-Vizi, Manju A Kurian, Robin Ketteler

Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission

肼屈嗪通过抑制 Drp1 介导的线粒体裂变保护心脏免受急性缺血/再灌注损伤

Siavash Beikoghli Kalkhoran, Janos Kriston-Vizi, Sauri Hernandez-Resendiz, Gustavo E Crespo-Avilan, Ayeshah A Rosdah, Jarmon G Lees, Joana Rodrigues Simoes Da Costa, Naomi X Y Ling, Jessica K Holien, Parisa Samangouei, Kroekkiat Chinda, En Ping Yap, Jaime A Riquelme, Robin Ketteler, Derek M Yellon, 

Transcriptional co-activators YAP1-TAZ of Hippo signalling in doxorubicin-induced cardiomyopathy

阿霉素诱发的心肌病中 Hippo 信号转录辅激活因子 YAP1-TAZ

Tünde Berecz, Angela Yiu, Orsolya Vittay, Barbara Orsolits, Maxime Mioulane, Cristobal G Dos Remedios, Robin Ketteler, Bela Merkely, Ágota Apáti, Sian E Harding, Nicola Hellen, Gabor Foldes

Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter

FDA 批准的线粒体钙单向转运体正向和负向调节剂的鉴定和功能验证

Agnese De Mario, Anna Tosatto, Julia Marie Hill, Janos Kriston-Vizi, Robin Ketteler, Denis Vecellio Reane, Gino Cortopassi, Gyorgy Szabadkai, Rosario Rizzuto, Cristina Mammucari

Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches

研究USP30抑制剂对增强Parkin介导的线粒体自噬的作用:工具和方法

Eliona Tsefou ,Alison S Walker ,Emily H Clark ,Amy R Hicks ,Christin Luft ,Kunitoshi Takeda ,Toru Watanabe ,Bianca Ramazio ,James M Staddon ,Thomas Briston ,Robin Ketteler

Modulation of endothelial organelle size as an antithrombotic strategy

调节内皮细胞器大小作为抗血栓策略

Francesco Ferraro, Francesca Patella, Joana R Costa, Robin Ketteler, Janos Kriston-Vizi, Daniel F Cutler

FBS/BSA media concentration determines CCCP's ability to depolarize mitochondria and activate PINK1-PRKN mitophagy

FBS/BSA 培养基浓度决定 CCCP 使线粒体去极化并激活 PINK1-PRKN 线粒体自噬的能力

Marc P M Soutar, Liam Kempthorne, Emily Annuario, Christin Luft, Selina Wray, Robin Ketteler, Marthe H R Ludtmann, Hélène Plun-Favreau

Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells

细胞中揭示了人类 ATG4 蛋白酶亚型在自噬和 LC3/GABARAP 加工中的冗余性

Alexander Agrotis,Niccolo Pengo,Jemima J Burden,Robin Ketteler

Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases

涉及 MET 和 FAK 的信号传导支持细胞分裂,而不依赖于细胞周期调节 CDK4/6 激酶的活性

Chi Zhang, Simon R Stockwell, May Elbanna, Robin Ketteler, Jamie Freeman, Bissan Al-Lazikani, Suzanne Eccles, Alexis De Haven Brandon, Florence Raynaud, Angela Hayes, Paul A Clarke, Paul Workman, Sibylle Mittnacht