日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope

GPU 加速发现病原体衍生的 T 细胞胰岛素表位分子模拟物

Thomas Whalley, Garry Dolton, Paul E Brown, Aaron Wall, Linda Wooldridge, Hugo van den Berg, Anna Fuller, Jade R Hopkins, Michael D Crowther, Meriem Attaf, Robin R Knight, David K Cole, Mark Peakman, Andrew K Sewell, Barbara Szomolay

Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity

自身反应性前胰岛素特异性 CD8 T 细胞杀伤人类 β 细胞主要是通过颗粒介导的,其效力取决于 T 细胞受体亲和力

Robin R Knight, Deborah Kronenberg, Min Zhao, Guo Cai Huang, Martin Eichmann, Anna Bulek, Linda Wooldridge, David K Cole, Andrew K Sewell, Mark Peakman, Ania Skowera

Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity

临床级多能成体祖细胞可在人类移植和自身免疫模型中持久控制致病性 T 细胞反应

James L Reading, Jennie H M Yang, Shereen Sabbah, Ania Skowera, Robin R Knight, Jef Pinxteren, Bart Vaes, Timothy Allsopp, Anthony E Ting, Sarah Busch, Amy Raber, Robert Deans, Timothy I M Tree

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

型糖尿病中 CD8(+) T 细胞杀死人类 β 细胞的结构基础

Anna M Bulek, David K Cole, Ania Skowera, Garry Dolton, Stephanie Gras, Florian Madura, Anna Fuller, John J Miles, Emma Gostick, David A Price, Jan W Drijfhout, Robin R Knight, Guo C Huang, Nikolai Lissin, Peter E Molloy, Linda Wooldridge, Bent K Jakobsen, Jamie Rossjohn, Mark Peakman, Pierre J Rizk