日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells

亚群和组织定义的 STAT5 阈值控制着固有淋巴细胞的稳态和功能。

Villarino, Alejandro V; Sciumè, Giuseppe; Davis, Fred P; Iwata, Shigeru; Zitti, Beatrice; Robinson, Gertraud W; Hennighausen, Lothar; Kanno, Yuka; O'Shea, John J

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions

信号转导和转录激活因子5 (STAT5) 旁系同源基因的剂量决定T细胞的效应和调节功能。

Villarino, Alejandro; Laurence, Arian; Robinson, Gertraud W; Bonelli, Michael; Dema, Barbara; Afzali, Behdad; Shih, Han-Yu; Sun, Hong-Wei; Brooks, Stephen R; Hennighausen, Lothar; Kanno, Yuka; O'Shea, John J

Mammary-specific gene activation is defined by progressive recruitment of STAT5 during pregnancy and the establishment of H3K4me3 marks

乳腺特异性基因激活的特征是妊娠期间STAT5的逐步募集和H3K4me3标记的建立。

Kang, Keunsoo; Yamaji, Daisuke; Yoo, Kyung Hyun; Robinson, Gertraud W; Hennighausen, Lothar

The gene encoding the hematopoietic stem cell regulator CCN3/NOV is under direct cytokine control through the transcription factors STAT5A/B.

编码造血干细胞调节因子 CCN3/NOV 的基因受细胞因子通过转录因子 STAT5A/B 的直接控制

Kimura 木村丹香子 Akiko, Martin Cyril, Robinson Gertraud W, Simone James M, Chen Weiping, Wickre Mark C, O'Shea John J, Hennighausen Lothar

Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression.

造血特异性 Stat5 基因敲除小鼠表现出小细胞低色素性贫血,伴有转铁蛋白受体基因表达降低

Zhu Bing-Mei, McLaughlin Sara K, Na Risu, Liu Jie, Cui Yongzhi, Martin Cyril, Kimura Akiko, Robinson Gertraud W, Andrews Nancy C, Hennighausen Lothar

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

通过转录因子 STAT5A 和 STAT5B 解读细胞因子信号传导

Hennighausen, Lothar; Robinson, Gertraud W

Nonredundant roles for Stat5a/b in directly regulating Foxp3

Stat5a/b 在直接调控 Foxp3 中发挥着不可替代的作用

Yao, Zhengju; Kanno, Yuka; Kerenyi, Marc; Stephens, Geoffrey; Durant, Lydia; Watford, Wendy T; Laurence, Arian; Robinson, Gertraud W; Shevach, Ethan M; Moriggl, Richard; Hennighausen, Lothar; Wu, Changyou; O'Shea, John J

The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging

转录因子Stat5a/b并非胰岛发育所必需,但会在衰老过程中调节胰腺β细胞的生理功能。

Lee, Ji-Yeon; Gavrilova, Oksana; Davani, Behrous; Na, Risu; Robinson, Gertraud W; Hennighausen, Lothar

Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function

急性髓系白血病相关Mkl1(Mrtf-a)是乳腺功能的关键调节因子

Sun, Yi; Boyd, Kelli; Xu, Wu; Ma, Jing; Jackson, Carl W; Fu, Amina; Shillingford, Jonathan M; Robinson, Gertraud W; Hennighausen, Lothar; Hitzler, Johann K; Ma, Zhigui; Morris, Stephan W

Identification of signaling pathways in early mammary gland development by mouse genetics

利用小鼠遗传学方法鉴定早期乳腺发育中的信号通路

Robinson, Gertraud W