日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Native and Denaturing MS Protein Deconvolution for Biopharma: Monoclonal Antibodies and Antibody-Drug Conjugates to Polydisperse Membrane Proteins and Beyond

天然和变性质谱蛋白质解卷积在生物制药领域的应用:从单克隆抗体和抗体-药物偶联物到多分散膜蛋白及其他

Campuzano, Iain D G; Robinson, John H; Hui, John O; Shi, Stone D-H; Netirojjanakul, Chawita; Nshanian, Michael; Egea, Pascal F; Lippens, Jennifer L; Bagal, Dhanashri; Loo, Joseph A; Bern, Marshall

Unconventional T-cell recognition of an arthritogenic epitope of proteoglycan aggrecan released from degrading cartilage

T细胞对从退化软骨中释放的蛋白聚糖聚集蛋白聚糖的致关节炎表位的非常规识别

Falconer, Jane; Mahida, Rahul; Venkatesh, Divya; Pearson, Jeffrey; Robinson, John H

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data

BIITE:一种利用T细胞ELISpot数据确定HLA II类表位的工具

Boelen, Lies; O'Neill, Patrick K; Quigley, Kathryn J; Reynolds, Catherine J; Maillere, Bernard; Robinson, John H; Lertmemongkolchai, Ganjana; Altmann, Daniel M; Boyton, Rosemary J; Asquith, Becca

Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+ T-cell activation

抗原特异性B淋巴细胞从软骨细胞外基质中获取蛋白聚糖聚集蛋白聚糖,从而导致抗原呈递和CD4+ T细胞活化。

Ciechomska, Marzena; Wilson, Caroline L; Floudas, Achilleas; Hui, Wang; Rowan, Andrew D; van Eden, Willem; Robinson, John H; Knight, Andrew M

Presentation of the candidate rheumatoid arthritis autoantigen aggrecan by antigen-specific B cells induces enhanced CD4(+) T helper type 1 subset differentiation

抗原特异性B细胞呈递候选类风湿性关节炎自身抗原聚集蛋白聚糖可诱导CD4(+)辅助性T细胞1型亚群分化增强。

Wilson, Caroline L; Hine, Dominic W; Pradipta, Ariel; Pearson, Jeffrey P; van Eden, Willem; Robinson, John H; Knight, Andrew M

Colony variability under the spotlight in animal models of arthritis

动物关节炎模型中菌落变异性成为关注焦点

Robinson, John H

T cell responses to a non-glycosylated epitope predominate in type II collagen-immunised HLA-DRB1*0101 transgenic mice.

在 II 型胶原蛋白免疫的 HLA-DRB1*0101 转基因小鼠中,针对非糖基化表位的 T 细胞反应占主导地位

von Delwig Alexei, Altmann Daniel M, Charlton Fraser G, McKie Norman, Isaacs John D, Holmdahl Rikard, Robinson John H

Mechanisms of major histocompatibility complex class II-restricted processing and presentation of the V antigen of Yersinia pestis.

鼠疫耶尔森氏菌V抗原主要组织相容性复合体II类限制性加工和呈递机制

Shim Ho-Ki, Musson Julie A, Harper Helen M, McNeill Hesta V, Walker Nicola, Flick-Smith Helen, von Delwig Alexei, Williamson E Diane, Robinson John H

Major histocompatibility class II molecules prevent destructive processing of exogenous peptides at the cell surface of macrophages for presentation to CD4 T cells

主要组织相容性复合体II类分子可防止巨噬细胞表面外源肽被破坏性加工,从而阻止其呈递给CD4 T细胞。

von Delwig, Alexei; Musson, Julie A; Gray, Joe; McKie, Norman; Robinson, John H