日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor

肽与小分子配体在阿扑素受体结合的结构和功能测定

Thomas L Williams #, Grégory Verdon #, Rhoda E Kuc, Heather Currinn, Brian Bender, Nicolae Solcan, Oliver Schlenker, Robyn G C Macrae, Jason Brown, Marco Schütz, Andrei Zhukov, Sanjay Sinha, Chris de Graaf, Stefan Gräf, Janet J Maguire, Alastair J H Brown, Anthony P Davenport

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

马凡氏综合征 iPSC 衍生的血管平滑肌细胞表型筛选发现 GSK3β 是新靶点

Hongorzul Davaapil, Madeline McNamara, Alessandra Granata, Robyn G C Macrae, Mei Hirano, Martina Fitzek, J A Aragon-Martin, Anne Child, David M Smith, Sanjay Sinha

Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands

使用新型荧光配体扩展阿扑素受体药理学工具箱

Thomas L Williams, Robyn G C Macrae, Rhoda E Kuc, Alastair J H Brown, Janet J Maguire, Anthony P Davenport

Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection

人类胚胎干细胞衍生的心肌细胞平台筛选 SARS-CoV-2 感染的抑制剂

Thomas L Williams #, Maria T Colzani #, Robyn G C Macrae, Emma L Robinson, Stuart Bloor, Edward J D Greenwood, Jun Ru Zhan, Gregory Strachan, Rhoda E Kuc, Duuamene Nyimanu, Janet J Maguire, Paul J Lehner, Sanjay Sinha, Anthony P Davenport

Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites

与缺乏 SARS-CoV-2 结合位点的短 deltaACE2 亚型相比,人类病毒进入受体 ACE2 的表达存在差异

Thomas L Williams, Gregory Strachan, Robyn G C Macrae, Rhoda E Kuc, Duuamene Nyimanu, Anna L Paterson, Sanjay Sinha, Janet J Maguire, Anthony P Davenport

International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand

国际基础与临床药理学联合会。CVII. Apelin受体的结构和药理学,并建议Elabela/Toddler是第二种内源性肽配体

Read, Cai; Nyimanu, Duuamene; Williams, Thomas L; Huggins, David J; Sulentic, Petra; Macrae, Robyn G C; Yang, Peiran; Glen, Robert C; Maguire, Janet J; Davenport, Anthony P