日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Enhancing KLF15 activity in cardiomyocytes: a novel approach to prevent pathological reprogramming and fibrosis via nuclease-deficient dCas9VPR

增强心肌细胞中 KLF15 的活性：一种通过核酸酶缺陷型 dCas9VPR 预防病理性重编程和纤维化的新方法

期刊:Signal Transduction and Targeted Therapy
影响因子:
doi:10.1038/s41392-026-02593-9
Schoger, Eric; Kim, Rosa; Bleckwedel, Federico; Peralta, Tomás M; Priesmeier, Laura; Fischer, Janek A; Stengel, Laura; Rocha, Cheila; Santos, Gabriela L; Lutz, Susanne; Boileau, Etienne; Baumgarten, Nina; Schulz, Marcel H; Dieterich, Christoph; Müller, Oliver J; Cyganek, Lukas; Cabrera-Orefice, Alfredo; Eberl, Hanna; Maack, Christoph; Streckfuss-Bömeke, Katrin; Pavez-Giani, Mario G; Doroudgar, Shirin; Sossalla, Samuel; Zelarayán, Laura C
KLF15
细胞生物学
发表日期：2026
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Simulations and active learning enable efficient identification of an experimentally-validated broad coronavirus inhibitor.

模拟和主动学习能够有效地识别经实验验证的广谱冠状病毒抑制剂

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62139-5
Elez Katarina, Hempel Tim, Shrimp Jonathan H, Moor Nicole, Raich Lluís, Rocha Cheila, Winter Robin, Le Tuan, Pöhlmann Stefan, Hoffmann Markus, Hall Matthew D, Noé Frank
信号转导
发表日期：2025
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Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D.

宿主细胞凝集素 ASGR1 和 DC-SIGN 与 TMEM106B 共同赋予 ACE2 非依赖性和对刺突蛋白突变 E484D 的 SARS-CoV-2 假病毒 imdevimab 的抗性

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.01230-24
Arora Prerna, Zhang Lu, Nehlmeier Inga, Kempf Amy, Graichen Luise, Kreitz Eike, Sidarovich Anzhalika, Rocha Cheila, Gärtner Sabine, Winkler Michael, Schulz Sebastian, Jäck Hans-Martin, Hoffmann Markus, Pöhlmann Stefan
细胞生物学
ACE2
发表日期：2025
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Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Omicron 亚变种 BA.1 的刺突蛋白中的氨基酸残基 655 和 969 控制着 TMPRSS2 与组织蛋白酶 L 依赖性入侵途径的使用以及细胞趋向性。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0328879
Rocha, Cheila; Arora, Prerna; Zhang, Lu; Sidarovich, Anzhalika; Graichen, Luise; Moldenhauer, Anna-Sophie; Pöhlmann, Stefan; Hoffmann, Markus
细胞生物学
发表日期：2025
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Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

作者更正：单细胞转录组学揭示病理重塑过程中具有心肌细胞蛋白稳态特征的细胞外囊泡分泌

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-024-06319-x
Schoger, Eric; Bleckwedel, Federico; Germena, Giulia; Rocha, Cheila; Tucholla, Petra; Sobitov, Izzatullo; Möbius, Wiebke; Sitte, Maren; Lenz, Christof; Samak, Mostafa; Hinkel, Rabea; Varga, Zoltán V; Giricz, Zoltán; Salinas, Gabriela; Gross, Julia C; Zelarayán, Laura C
囊泡
细胞生物学
单细胞
发表日期：2024
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Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity"

对“靶向组织蛋白酶的SARS-CoV-2抑制剂：设计、合成和生物活性”的更正

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00095
Flury, Philipp; Breidenbach, Julian; Krüger, Nadine; Voget, Rabea; Schäkel, Laura; Si, Yaoyao; Krasniqi, Vesa; Calistri, Sara; Olfert, Matthias; Sylvester, Katharina; Rocha, Cheila; Ditzinger, Raphael; Rasch, Alexander; Pöhlmann, Stefan; Kronenberger, Thales; Poso, Antti; Rox, Katharina; Laufer, Stefan A; Müller, Christa E; Gütschow, Michael; Pillaiyar, Thanigaimalai
SARS-CoV-2
发表日期：2024
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Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

多价纳米凝集素通过靶向病毒刺突蛋白上的糖基化基团，有效中和SARS-CoV-2病毒。

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.3c00163
Budhadev, Darshita; Hooper, James; Rocha, Cheila; Nehlmeier, Inga; Kempf, Amy Madeleine; Hoffmann, Markus; Krüger, Nadine; Zhou, Dejian; Pöhlmann, Stefan; Guo, Yuan
微生物学
SARS-CoV-2
发表日期：2023
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Discovery of Polyphenolic Natural Products as SARS-CoV-2 M(pro) Inhibitors for COVID-19

发现多酚类天然产物作为SARS-CoV-2 M(pro)抑制剂用于治疗COVID-19

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph16020190
Krüger, Nadine; Kronenberger, Thales; Xie, Hang; Rocha, Cheila; Pöhlmann, Stefan; Su, Haixia; Xu, Yechun; Laufer, Stefan A; Pillaiyar, Thanigaimalai
SARS-CoV-2
发表日期：2023
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Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3

SARS-CoV-2 omicron 亚型 BA.1、BA.2 和 BA.3 具有相似的中和逃避能力

期刊:Lancet Infectious Diseases
影响因子:31
doi:10.1016/S1473-3099(22)00224-9
Arora, Prerna; Zhang, Lu; Rocha, Cheila; Sidarovich, Anzhalika; Kempf, Amy; Schulz, Sebastian; Cossmann, Anne; Manger, Bernhard; Baier, Eva; Tampe, Björn; Moerer, Onnen; Dickel, Steffen; Dopfer-Jablonka, Alexandra; Jäck, Hans-Martin; Behrens, Georg M N; Winkler, Martin S; Pöhlmann, Stefan; Hoffmann, Markus
SARS-CoV-2
发表日期：2022
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Investigations on SARS-CoV-2 Susceptibility of Domestic and Wild Animals Using Primary Cell Culture Models Derived from the Upper and Lower Respiratory Tract.

利用源自上呼吸道和下呼吸道的原代细胞培养模型，研究家畜和野生动物对 SARS-CoV-2 的易感性

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v14040828
Färber Iris, Krüger Johannes, Rocha Cheila, Armando Federico, von Köckritz-Blickwede Maren, Pöhlmann Stefan, Braun Armin, Baumgärtner Wolfgang, Runft Sandra, Krüger Nadine
细胞生物学
新冠
发表日期：2022
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