日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of Sulfonamide Pantothenate Kinase Activators and Elucidation of the Role of Isoform Selectivity in Cellular Pantothenate Kinase Activation

磺胺类泛酸激酶激活剂的发现及同工酶选择性在细胞泛酸激酶激活中的作用阐明

Coker, Ashton L; Tangallapally, Rajendra; Yun, Mi-Kyung; Subramanian, Chitra; Jayasinghe, Thilina; Miller, Karen; Edwards, Anne; Frank, Matthew; Jackowski, Suzanne; Rock, Charles O; White, Stephen W; Lee, Richard E

Isoleucine Binding and Regulation of Escherichia coli and Staphylococcus aureus Threonine Dehydratase (IlvA)

异亮氨酸结合及大肠杆菌和金黄色葡萄球菌苏氨酸脱水酶(IlvA)的调控

Yun, Mi-Kyung; Subramanian, Chitra; Miller, Karen; Jackson, Pamela; Radka, Christopher D; Rock, Charles O

Staphylococcus aureus oleate hydratase produces ligands that activate host PPARα.

金黄色葡萄球菌油酸水合酶产生配体,激活宿主PPARα

Radka Christopher D, Frank Matthew W, Simmons Tyler S, Johnson Cydney N, Rosch Jason W, Rock Charles O

The Bacillus subtilis cell envelope stress-inducible ytpAB operon modulates membrane properties and contributes to bacitracin resistance

枯草芽孢杆菌细胞包膜应激诱导型ytpAB操纵子调节膜特性并导致杆菌肽耐药性。

Willdigg, Jessica R; Patel, Yesha; Arquilevich, Briana E; Subramanian, Chitra; Frank, Matthew W; Rock, Charles O; Helmann, John D

Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis

枯草芽孢杆菌中脂肪酸生物合成起始酶的晶体结构

Radka, Christopher D; Rock, Charles O

Cryo-EM reconstruction of oleate hydratase bound to a phospholipid membrane bilayer

冷冻电镜重构油酸水合酶与磷脂膜双层的结合

Oldham, Michael L; Zuhaib Qayyum, M; Kalathur, Ravi C; Rock, Charles O; Radka, Christopher D

A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus

金黄色葡萄球菌中支持支链脂肪酸合成的短链酰基辅酶A合成酶

Whaley, Sarah G; Frank, Matthew W; Rock, Charles O

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

抗生素敏感性靶点和耐受途径的全基因组图谱

Leshchiner, Dmitry; Rosconi, Federico; Sundaresh, Bharathi; Rudmann, Emily; Ramirez, Luisa Maria Nieto; Nishimoto, Andrew T; Wood, Stephen J; Jana, Bimal; Buján, Noemí; Li, Kaicheng; Gao, Jianmin; Frank, Matthew; Reeve, Stephanie M; Lee, Richard E; Rock, Charles O; Rosch, Jason W; van Opijnen, Tim

Mining Fatty Acid Biosynthesis for New Antimicrobials

挖掘脂肪酸生物合成途径以获取新型抗菌剂

Radka, Christopher D; Rock, Charles O

Proton magnetic resonance spectroscopy detects cerebral metabolic derangement in a mouse model of brain coenzyme a deficiency

质子磁共振波谱法可检测脑辅酶A缺乏症小鼠模型中的脑代谢紊乱。

Li, Yanan; Steinberg, Jeffrey; Coleman, Zane; Wang, Shubo; Subramanian, Chitra; Li, Yimei; Patay, Zoltan; Akers, Walter; Rock, Charles O; Jackowski, Suzanne; Bagga, Puneet