日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Tandem Ring Closure and Nitrobenzene Reduction with Sulfide Provides an Improved Route to an Important Intermediate for the Anti-Tuberculosis Drug Candidate Sutezolid

串联环化反应和硫醚还原硝基苯为抗结核候选药物苏特唑胺的重要中间体提供了一条改进的合成路线。

Kalmode, Hanuman P; Ravikumar, Ongolu; Paymode, Dinesh J; Bachert, John; Burns, Justina M; Stringham, Rodger W; Aleshire, Sarah L; Nelson, Ryan C

Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline

应用手性转移试剂提高抗结核药物贝达喹啉合成的立体选择性和产率

Robey, Juliana M S; Maity, Sanjay; Aleshire, Sarah L; Ghosh, Angshuman; Yadaw, Ajay K; Roy, Subho; Mear, Sarah Jane; Jamison, Timothy F; Sirasani, Gopal; Senanayake, Chris H; Stringham, Rodger W; Gupton, B Frank; Donsbach, Kai O; Nelson, Ryan C; Shanahan, Charles S

Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir

瑞德西韦吡咯并[2,1-f][1,2,4]三嗪的简便可扩展合成方法

Roy, Sarabindu; Yadaw, Ajay; Roy, Subho; Sirasani, Gopal; Gangu, Aravind; Brown, Jack D; Armstrong, Joseph D 3rd; Stringham, Rodger W; Gupton, B Frank; Senanayake, Chris H; Snead, David R

Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis

从胞苷出发,开发一种实用、非酶法合成用于研究的COVID-19抗病毒药物莫努匹拉韦的方法:以供应为中心的合成

Gopalsamuthiram, Vijayagopal; Kadam, Appasaheb L; Noble, Jeffrey K; Snead, David R; Williams, Corshai; Jamison, Timothy F; Senanayake, Chris; Yadaw, Ajay K; Roy, Sarabindu; Sirasani, Gopal; Gupton, B Frank; Burns, Justina; Cook, Daniel W; Stringham, Rodger W; Ahmad, Saeed; Krack, Rudy

Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis

通过改进吡咯并三嗪合成法扩大瑞德西韦的获取途径:以供应为中心的合成

Paymode, Dinesh J; Cardoso, Flavio S P; Agrawal, Toolika; Tomlin, John W; Cook, Daniel W; Burns, Justina M; Stringham, Rodger W; Sieber, Joshua D; Gupton, B Frank; Snead, David R

An Economical Route to Lamivudine Featuring a Novel Strategy for Stereospecific Assembly

一种经济高效的拉米夫定合成路线,采用新型立体特异性组装策略

Snead, David R; McQuade, D Tyler; Ahmad, Saeed; Krack, Rudy; Stringham, Rodger W; Burns, Justina M; Abdiaj, Irini; Gopalsamuthiram, Vijayagopal; Nelson, Ryan C; Gupton, B Frank

Synthesis of an Oxathiolane Drug Substance Intermediate Guided by Constraint-Driven Innovation

约束驱动创新指导下的氧硫杂环戊烷药物中间体的合成

Kashinath, K; Snead, David R; Burns, Justina M; Stringham, Rodger W; Gupton, B Frank; McQuade, D Tyler

Practical Synthesis of the Bicyclic Darunavir Side Chain: (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol from Monopotassium Isocitrate

双环达芦那韦侧链的实用合成:由异柠檬酸单钾合成(3R,3aS,6aR)-六氢呋喃并[2,3-b]呋喃-3-醇

Moore, Gary L; Stringham, Rodger W; Teager, David S; Yue, Tai-Yuen