日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities

纤维板层癌中异常增强子活性的热点区域揭示了候选致癌通路和治疗弱点

Timothy A Dinh,Ramja Sritharan,F Donelson Smith,Adam B Francisco,Rosanna K Ma,Rodica P Bunaciu,Matt Kanke,Charles G Danko,Andrew P Massa,John D Scott,Praveen Sethupathy

Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

体内急性抑制胰岛素抵抗相关的肝脏miR-29可改善成年小鼠的血糖控制。

Hung, Yu-Han; Kanke, Matt; Kurtz, C Lisa; Cubitt, Rebecca; Bunaciu, Rodica P; Miao, Ji; Zhou, Liye; Graham, James L; Hussain, M Mahmood; Havel, Peter; Biddinger, Sudha; White, Phillip J; Sethupathy, Praveen

Retinoic acid and 6-formylindolo(3,2-b)carbazole (FICZ) combination therapy reveals putative targets for enhancing response in non-APL AML

维甲酸和 6-甲酰吲哚 (3,2-b) 咔唑 (FICZ) 联合疗法揭示了增强非 APL AML 疗效的推定靶点

Rodica P Bunaciu, Robert J MacDonald, Holly A Jensen, Feng Gao, Xin Wang, Lynn Johnson, Jeffrey D Varner, Andrew Yen

Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells

Src家族激酶抑制剂博舒替尼可增强维甲酸诱导的HL-60白血病细胞分化。

MacDonald, Robert J; Bunaciu, Rodica P; Ip, Victoria; Dai, David; Tran, David; Varner, Jeffrey D; Yen, Andrew

The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells

c-Raf 调节剂 RRD-251 增强核 c-Raf/GSK-3/VDR 轴信号传导并增强 1,25-二羟基维生素 D3 诱导的 HL-60 髓细胞白血病细胞分化

Harrison T Supnick, Rodica P Bunaciu, Andrew Yen

An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program

视黄酸诱导HL-60分化程序的有效模型

Ryan Tasseff, Holly A Jensen, Johanna Congleton, David Dai, Katharine V Rogers, Adithya Sagar, Rodica P Bunaciu, Andrew Yen, Jeffrey D Varner

Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment

wt-NPM1 原发性 AML 细胞亚群对视黄酸治疗有反应的可能性

Rodica P Bunaciu, Robert J MacDonald, Feng Gao, Lynn M Johnson, Jeffrey D Varner, Xin Wang, Sarah Nataraj, Monica L Guzman, Andrew Yen

RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

RRD-251 增强全反式维甲酸 (RA) 诱导的 HL-60 髓系白血病细胞分化

Aaron S Wallace, Harrison T Supnick, Rodica P Bunaciu, Andrew Yen

GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation

GW5074 和 PP2 激酶抑制剂表明,非传统的 c-Raf 和 Lyn 功能是视黄酸诱导成熟的驱动因素。

Jensen, Holly A; Bunaciu, Rodica P; Varner, Jeffrey D; Yen, Andrew

6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells

6-甲酰吲哚(3,2-b)咔唑 (FICZ) 调节负责 RA 诱导的 HL-60 髓细胞白血病细胞分化的信号体

Rodica P Bunaciu, Holly A Jensen, Robert J MacDonald, Dorian H LaTocha, Jeffrey D Varner, Andrew Yen