日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Whole genome sequencing improves tissue-of-origin diagnosis and treatment options for cancer of unknown primary

全基因组测序可改善原发灶不明癌症的组织来源诊断和治疗选择。

Richard J Rebello # ,Atara Posner # ,Ruining Dong ,Owen W J Prall ,Tharani Sivakumaran ,Camilla B Mitchell ,Aidan Flynn ,Alex Caneborg ,Catherine Mitchell ,Sehrish Kanwal ,Clare Fedele ,Samantha Webb ,Krista Fisher ,Hui-Li Wong ,Shiva Balachander ,Wenying Zhu ,Shannon Nicolson ,Voula Dimitriadis ,Nicholas Wilcken ,Anna DeFazio ,Bo Gao ,Madhu Singh ,Ian M Collins ,Christopher Steer ,Mark Warren ,Narayan Karanth ,Huiling Xu ,Andrew Fellowes ,Rodney J Hicks ,Kym Pham Stewart ,Charles Shale ,Peter Priestley ,Sarah-Jane Dawson ,Joseph H A Vissers ,Stephen B Fox ,Penelope Schofield ,David Bowtell ,Oliver Hofmann ,Sean M Grimmond ,Linda Mileshkin ,Richard W Tothill

Preclinical evaluation and automated synthesis of [89Zr]ZrDFOSquaramide-girentuximab for diagnostic imaging of carbonic anhydrase IX positive tumours

[89Zr]ZrDFOSquaramide-girentuximab 的临床前评估和自动合成,用于碳酸酐酶 IX 阳性肿瘤的诊断成像

Asif Noor, Emily R McGowan, Jessica K Van Zuylekom, Carleen Cullinane, Peter D Roselt, Rodney J Hicks, Michael P Wheatcroft, Paul S Donnelly

A genome-wide CRISPR/Cas9 screen identifies DNA-PK as a sensitiser to 177Lutetium-DOTA-octreotate radionuclide therapy

全基因组 CRISPR/Cas9 筛选确定 DNA-PK 是 177Lutetium-DOTA-octreotate 放射性核素治疗的敏感剂

Kelly Waldeck, Jessica Van Zuylekom, Carleen Cullinane, Twishi Gulati, Kaylene J Simpson, Richard W Tothill, Benjamin Blyth, Rodney J Hicks

Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment

嗜铬细胞瘤和副神经节瘤的单核和大量组织基因表达分析将疾病亚型与肿瘤微环境联系起来

Magnus Zethoven #, Luciano Martelotto #, Andrew Pattison #, Blake Bowen #, Shiva Balachander, Aidan Flynn, Fernando J Rossello, Annette Hogg, Julie A Miller, Zdenek Frysak, Sean Grimmond, Lauren Fishbein, Arthur S Tischler, Anthony J Gill, Rodney J Hicks, Patricia L M Dahia, Roderick Clifton-Bligh, 

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma

BRAFV600黑色素瘤中代谢的适应性翻译重编程限制了靶向治疗的反应。

Lorey K Smith ,Tiffany Parmenter ,Margarete Kleinschmidt ,Eric P Kusnadi ,Jian Kang ,Claire A Martin ,Peter Lau ,Riyaben Patel ,Julie Lorent ,David Papadopoli ,Anna Trigos ,Teresa Ward ,Aparna D Rao ,Emily J Lelliott ,Karen E Sheppard ,David Goode ,Rodney J Hicks ,Tony Tiganis ,Kaylene J Simpson ,Ola Larsson ,Benjamin Blythe ,Carleen Cullinane ,Vihandha O Wickramasinghe ,Richard B Pearson ,Grant A McArthur

First clinical study of a pegylated diabody 124I-labeled PEG-AVP0458 in patients with tumor-associated glycoprotein 72 positive cancers

聚乙二醇化双抗体 124I 标记 PEG-AVP0458 针对肿瘤相关糖蛋白 72 阳性癌症患者的首次临床研究

Andrew M Scott, Timothy Akhurst, Fook-Thean Lee, Marika Ciprotti, Ian D Davis, Andrew J Weickhardt, Hui K Gan, Rodney J Hicks, Sze Ting Lee, Pece Kocovski, Nancy Guo, Maggie Oh, Linda Mileshkin, Scott Williams, Declan Murphy, Kunthi Pathmaraj, Graeme J O'Keefe, Sylvia J Gong, John S Pedersen, Fiona

Enhancing the anti-tumour activity of 177Lu-DOTA-octreotate radionuclide therapy in somatostatin receptor-2 expressing tumour models by targeting PARP

通过靶向 PARP 增强 177Lu-DOTA-奥曲肽放射性核素治疗在生长抑素受体 2 表达肿瘤模型中的抗肿瘤活性

Carleen Cullinane #, Kelly Waldeck #, Laura Kirby, Buck E Rogers, Peter Eu, Richard W Tothill, Rodney J Hicks

Cold Kit for Prostate-Specific Membrane Antigen (PSMA) PET Imaging: Phase 1 Study of 68Ga-Tris(Hydroxypyridinone)-PSMA PET/CT in Patients with Prostate Cancer

用于前列腺特异性膜抗原 (PSMA) PET 成像的冷试剂盒:68Ga-Tris(羟基吡啶酮)-PSMA PET/CT 在前列腺癌患者中的 I 期研究

Michael S Hofman ,Peter Eu ,Price Jackson ,Emily Hong ,David Binns ,Amir Iravani ,Declan Murphy ,Catherine Mitchell ,Shankar Siva ,Rodney J Hicks ,Jennifer D Young ,Philip J Blower ,Gregory E Mullen

Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model

长期持续暴露于帕比司他可诱导 TH-MYCN 神经母细胞瘤小鼠模型的终末分化和长期存活

Kelly Waldeck, Carleen Cullinane, Kerry Ardley, Jake Shortt, Ben Martin, Richard W Tothill, Jason Li, Ricky W Johnstone, Grant A McArthur, Rodney J Hicks, Paul J Wood

New Tris(hydroxypyridinone) Bifunctional Chelators Containing Isothiocyanate Groups Provide a Versatile Platform for Rapid One-Step Labeling and PET Imaging with (68)Ga(3.)

含异硫氰酸酯基团的新型三(羟基吡啶酮)双功能螯合剂为(68)Ga(3)快速一步标记和 PET 成像提供了多功能平台

Michelle T Ma, Carleen Cullinane, Cinzia Imberti, Julia Baguña Torres, Samantha Y A Terry, Peter Roselt, Rodney J Hicks, Philip J Blower