日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Repair of replication-dependent double-strand breaks differs between the leading and lagging strands

复制依赖性双链断裂的修复在先导链和滞后链之间存在差异。

Michael T Kimble ,Aakanksha Sane ,Robert J D Reid ,Matthew J Johnson ,Rodney Rothstein ,Lorraine S Symington

Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors

异常的 DNA 修复揭示了组蛋白 H3.3 突变脑肿瘤的脆弱性

Giulia Giacomini, Sandra Piquet, Odile Chevallier, Juliette Dabin, Siau-Kun Bai, Byungjin Kim, Robert Siddaway, Brian Raught, Etienne Coyaud, Chun-Min Shan, Robert J D Reid, Takenori Toda, Rodney Rothstein, Viviana Barra, Therese Wilhelm, Sabah Hamadat, Chloé Bertin, Alexander Crane, Frank Dubois, I

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability

Rad5 失调导致复制叉处重组过度活跃,从而导致顺铂敏感性和基因组不稳定

Eric E Bryant, Ivana Šunjevarić, Luke Berchowitz, Rodney Rothstein, Robert J D Reid

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers

未折叠蛋白反应应激传感器 ERN1 在调节 KRAS 突变结肠癌对 MEK 抑制剂的反应中的作用

Tonći Šuštić #, Sake van Wageningen #, Evert Bosdriesz, Robert J D Reid, John Dittmar, Cor Lieftink, Roderick L Beijersbergen, Lodewyk F A Wessels, Rodney Rothstein, René Bernards

Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability

Xrs2 和 Tel1 各自独立地促进 MR 介导的 DNA 连接和复制体稳定性

Julyun Oh ,So Jung Lee ,Rodney Rothstein ,Lorraine S Symington

CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

CRISPR 介导的碱基编辑可通过诱导终止密码子有效破坏真核基因

Pierre Billon, Eric E Bryant, Sarah A Joseph, Tarun S Nambiar, Samuel B Hayward, Rodney Rothstein, Alberto Ciccia

Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions

Srs2 过表达揭示了复制叉中不依赖解旋酶的作用,需要多种细胞功能

Ana María León Ortiz, Robert J D Reid, John C Dittmar, Rodney Rothstein, Alain Nicolas

Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination

Rad52 氨基末端 DNA 结合活性在同源重组中 DNA 链捕获中的作用

Idina Shi, Swee C L Hallwyl, Changhyun Seong, Uffe Mortensen, Rodney Rothstein, Patrick Sung

Alu elements mediate MYB gene tandem duplication in human T-ALL

Alu元件介导人类T细胞急性淋巴细胞白血病(T-ALL)中MYB基因的串联重复。

Jennifer O'Neil,Joelle Tchinda, Alejandro Gutierrez, Lisa Moreau, Richard S Maser, Kwok-Kin Wong, Wei Li, Keith McKenna, X Shirley Liu, Bin Feng, Donna Neuberg, Lewis Silverman, Daniel J DeAngelo, Jeffery L Kutok, Rodney Rothstein, Ronald A DePinho, Lynda Chin, Charles Lee, A Thomas Look

A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52

酵母 Rad52 进化保守的 N 端的分子遗传学解析

Uffe H Mortensen, Naz Erdeniz, Qi Feng, Rodney Rothstein