日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation.

白血病中发现的 SETD2 L1609P 突变会破坏甲基转移酶活性,降低组蛋白 H3K36 三甲基化。

Michail Christina, Berthelet Jérémy, Mechaly Ariel E, Bui Linh-Chi, Yang Haopeng, Cai Duo, Al Mahi Amira, Xie Aowei, Bisio Valeria, Sirri Valentina, Dupret Jean-Marie, Guidez Fabien, Xu Ximing, Joly Nicolas, Regad Leslie, Viguier Mireille, Deshayes Frédérique, Dulphy Nicolas, Green Michael R, Haouz Ahmed, Rodrigues Lima Fernando

Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

CREBBP突变淋巴瘤中CD40反应性增强子激活减弱可通过强制CD4 T细胞参与来恢复。

Yang, Haopeng; Zhang, Wenchao; Ravanmehr, Vida; Cui, Guiling; Bowman, Kevin; Chen, Ruidong; Henderson, Jared M; Lockman, Shyanne; Rojas, Estela; Wilson, Ashley; Parsons, Sydney; Mechaly, Ariel; Regad, Leslie; Haouz, Ahmed; Flowers, Christopher R; Neelapu, Sattva; Nastoupil, Loretta; Davis, R Eric; Deng, Qing; Rodrigues-Lima, Fernando; Green, Michael R

Structure and function of the lysine methyltransferase SETD2 in cancer: From histones to cytoskeleton

赖氨酸甲基转移酶SETD2在癌症中的结构和功能:从组蛋白到细胞骨架

Michail, Christina; Rodrigues Lima, Fernando; Viguier, Mireille; Deshayes, Frédérique

Loss of WNT2B Results in Epithelial Defects and Predisposes to Gastrointestinal Dysplasia in Humans

WNT2B 的缺失会导致上皮缺陷,并使人类易患胃肠道发育不良。

Lori, Leslie; Neuranter, Valentin; Lebreton, Corinne; Berthelet, Jérémy; Parlato, Marianna; Michail, Christina; Khiat, Anis; Berrebi, Dominique; Bruneau, Julie; Terris, Benoit; Malamut, Georgia; Hanein, Sylvain; Schmitt, Yohann; Banal, Céline; Rodrigues Lima, Fernando; Azouguene, Emilie; Ruemmele, Frank; Talbotec, Cecile; Lambe, Cecile; Cerf-Bensussan, Nadine; Charbit-Henrion, Fabienne

Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase.

CREB结合蛋白(CREBBP)作为组蛋白丙酰转移酶的结构和功能表征

Cui Guiling, Ley Marie, Mechaly Ariel E, Bui Linh-Chi, Michail Christina, Berthelet Jérémy, Dairou Julien, Yang Haopeng, Chevreux Guillaume, Moroy Gautier, Green Michael R, Haouz Ahmed, Rodrigues Lima Fernando

U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review)

U2AF1 在多种肿瘤疾病中的作用及针对复杂突变恶性肿瘤的相关靶向治疗(综述)

Nian, Qing; Li, Yihui; Li, Jingwei; Zhao, Liyun; Rodrigues Lima, Fernando; Zeng, Jinhao; Liu, Rongxing; Ye, Zhijun

Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder

作者更正:CBP-HSF2 在 Rubinstein-Taybi 神经发育障碍中的结构和功能相互作用

de Thonel, Aurélie; Ahlskog, Johanna K; Daupin, Kevin; Dubreuil, Véronique; Berthelet, Jérémy; Chaput, Carole; Pires, Geoffrey; Leonetti, Camille; Abane, Ryma; Barris, Lluís Cordón; Leray, Isabelle; Aalto, Anna L; Naceri, Sarah; Cordonnier, Marine; Benasolo, Carène; Sanial, Matthieu; Duchateau, Agathe; Vihervaara, Anniina; Puustinen, Mikael C; Miozzo, Federico; Fergelot, Patricia; Lebigot, Élise; Verloes, Alain; Gressens, Pierre; Lacombe, Didier; Gobbo, Jessica; Garrido, Carmen; Westerheide, Sandy D; David, Laurent; Petitjean, Michel; Taboureau, Olivier; Rodrigues-Lima, Fernando; Passemard, Sandrine; Sabéran-Djoneidi, Délara; Nguyen, Laurent; Lancaster, Madeline; Sistonen, Lea; Mezger, Valérie

Interplay between EGFR, E-cadherin, and PTP1B in epidermal homeostasis

表皮稳态中 EGFR、E-钙黏蛋白和 PTP1B 之间的相互作用

Arnaud, Tessa; Rodrigues-Lima, Fernando; Viguier, Mireille; Deshayes, Frédérique

Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy

对导致极早发性自身免疫性肠病的人类蛋白酪氨酸磷酸酶PTPN2致病突变体(Cys216Gly)进行结构表征

Nian, Qing; Berthelet, Jérémy; Parlato, Marianna; Mechaly, Ariel E; Liu, Rongxing; Dupret, Jean-Marie; Cerf-Bensussan, Nadine; Haouz, Ahmed; Rodrigues Lima, Fernando

Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives

人蛋白酪氨酸磷酸酶1B (PTP1B):从结构到临床抑制剂的展望

Liu, Rongxing; Mathieu, Cécile; Berthelet, Jérémy; Zhang, Wenchao; Dupret, Jean-Marie; Rodrigues Lima, Fernando