日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged App (NL-G-F) mice

老年App(NL-GF)小鼠内侧内嗅皮层空间编码受损和神经元过度活跃

Rodriguez, Gustavo A; Rothenberg, Eva F; Shetler, C Oliver; Aoun, Andrew; Posani, Lorenzo; Vajram, Srujan V; Tedesco, Thomas; Fusi, Stefano; Hussaini, S Abid

Beyond correlation: optimal transport metrics for characterizing representational stability and remapping in neurons encoding spatial memory

超越相关性:表征空间记忆编码神经元中表征稳定性和重映射的最佳传输指标

Aoun, Andrew; Shetler, Oliver; Raghuraman, Radha; Rodriguez, Gustavo A; Hussaini, S Abid

Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus

化学遗传学方法减弱内嗅皮层神经元活动可减少海马体中的Aβ和tau蛋白病理。

Rodriguez, Gustavo A; Barrett, Geoffrey M; Duff, Karen E; Hussaini, S Abid

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease.

Tau蛋白病理导致兴奋性神经元丢失、网格细胞功能障碍和空间记忆缺陷,类似于早期阿尔茨海默病

Fu Hongjun, Rodriguez Gustavo A, Herman Mathieu, Emrani Sheina, Nahmani Eden, Barrett Geoffrey, Figueroa Helen Y, Goldberg Eliana, Hussaini S Abid, Duff Karen E

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

在小鼠Aβ沉积模型中,人类APOE4基因可增强Aβ斑块处小胶质细胞的反应性。

Rodriguez, Gustavo A; Tai, Leon M; LaDu, Mary Jo; Rebeck, G William

Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model

人类APOE基因型影响慢病毒基因转移模型中神经元内Aβ1-42的积累

Zhao, Wenjuan; Dumanis, Sonya B; Tamboli, Irfan Y; Rodriguez, Gustavo A; Jo Ladu, Mary; Moussa, Charbel E H; William Rebeck, G

Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex

年轻的APOE4靶向替换小鼠表现出较差的空间学习和记忆能力,内侧内嗅皮层的树突棘密度降低。

Rodriguez, Gustavo A; Burns, Mark P; Weeber, Edwin J; Rebeck, G William