日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Catabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response

丝氨酸对映体的分解代谢通过调节氮应激反应抑制肠出血性大肠杆菌的毒力因子

Addington, Emily; Wale, Kabo R; Horsburgh, Emily; Fargeas, Margot; Spathis, Leonidas; Leśniak, Weronika; Flavin, Saoirse; Rimbi, Patricia T; Mark, David R; Sandalli, Sofia; Serrano, Ester; Blackburn, Gavin; Regnault, Clément; Whitfield, Phillip D; Connolly, James P R; Roe, Andrew J; O'Boyle, Nicky

MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway

MYCN通过破坏PKA信号通路抑制神经母细胞瘤细胞中TrkC介导的分化。

Maher, Stephanie; Roe, Andrew; Wynne, Kieran; Zhernovkov, Vadim; Halasz, Melinda

Inhibition of HDAC6 alters fumarate hydratase activity and mitochondrial structure.

抑制 HDAC6 会改变延胡索酸水合酶活性和线粒体结构

Roe Andrew, Dowling Catríona M, D'Arcy Cian, Alencar Rodrigues Daniel, Wang Yu, Hiller Matthew, Keogh Carl, Hollinshead Kate E R, Garre Massimiliano, Cavanagh Brenton, Wynne Kieran, Liu Tianyan, Chen Zhixing, Kerr Emma, McIlroy Marie, H M Prehn Jochen, Schoen Ingmar, Chonghaile Tríona Ní

Enterohaemorrhagic Escherichia coli AdhE spirosome length correlates with enzymatic directionality and is perturbed by salicylidene acylhydrazides

肠出血性大肠杆菌 AdhE 螺旋体长度与酶促反应方向性相关,并受水杨酰肼类化合物的干扰。

Serrano, Ester; Zhao, Tianxiao; Mark, David R; Soroor, Mostafa; Floria, Iris; Terrill, Nicholas J; Kapur, Nikil; Tyler, Arwen I I; Horrocks, Mathew H; Roe, Andrew J; Byron, Olwyn

Genomic islands in Pseudomonas encode modular hotspots of defence and anti-defence systems

假单胞菌基因组岛编码防御和反防御系统的模块化热点。

Garrett, Stephen R; Tucker, Samantha K; Pavelka, Vojtech; Roe, Andrew J; Mariano, Giuseppina

Metabolomics for the Diagnosis of Secondary Infections in Critically Ill Patients With COVID-19

代谢组学在新冠肺炎重症患者继发感染诊断中的应用

McCreath, Gordan; Regnault, Clément; Blackburn, Gavin J; Daly, Rónán; Leanord, Alistair T; Whitfield, Phillip D; Roe, Andrew J; Davidson, Alan; Watson, Malcolm J; Sim, Malcolm A B

A 3D-printed optical microscope for low-cost histological imaging

一种用于低成本组织学成像的3D打印光学显微镜

Christopher, Jay; Craig, Rebecca; McHugh, Rebecca E; Roe, Andrew J; Bauer, Ralf; Patton, Brian; McConnell, Gail; Rooney, Liam M

Evaluating the protective effects of Aurodox in a murine model of Shiga toxin-producing Escherichia coli.

在产志贺毒素大肠杆菌小鼠模型中评估 Aurodox 的保护作用

McHugh Rebecca E, Rooney Liam M, Mark David R, Wale Kabo R, Clapperton Megan, McConnell Gail, Hoskisson Paul A, Douce Gillian R, Roe Andrew J

Steroid-free combination of 5-azacytidine and venetoclax for the treatment of multiple myeloma

用于治疗多发性骨髓瘤的5-氮胞苷和维奈托克无激素联合疗法

Flanagan, Lyndsey; Coughlan, Aisling; Cosgrove, Nicola; Roe, Andrew; Wang, Yu; Gilmore, Stephanie; Drozdz, Izabela; Comerford, Claire; Ryan, Jeremy; Minihane, Emma; Parvin, Salma; O'Dwyer, Michael; Quinn, John; Murphy, Philip; Furney, Simon; Glavey, Siobhan; Chonghaile, Tríona Ní; Foundation, Leukemia Research; Ireland, Science Foundation; Research, Breakthrough Cancer

A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens.

中心碳代谢的主调节因子直接激活附着和侵蚀性病原体的毒力基因表达

Wale Kabo R, O'Boyle Nicky, McHugh Rebecca E, Serrano Ester, Mark David R, Douce Gillian R, Connolly James P R, Roe Andrew J