日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

HMB-002: a monovalent antibody that elevates circulating VWF and FVIII levels for treatment of von Willebrand disease

HMB-002：一种单价抗体，可提高循环中VWF和FVIII水平，用于治疗血管性血友病。

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2025018516
Häger, Mattias; Zivkovic, Minka; Gandhi, Prafull S; Rasmussen, Caroline; Bonvoisin, Cécile; Harrison, Rane A; Poulsen, Emil; Huskens, Dana; Roest, Mark; Ferrara, Fortunato; Naretto, Anais; Renaud, Lionel; Olsen, Ole H; Eskesen, Nicolas O; Holten-Andersen, Lars; Malladi, Ruthvik; Rea, Catherine J; Sørensen, Benny; Urbanus, Rolf T; Østergaard, Henrik
VWF
发表日期：2026
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Predicting dialyzer fiber blocking is hard due to high intrapatient variability and limited utility of thrombin generation markers

由于患者个体差异较大以及凝血酶生成标志物的效用有限，预测透析器纤维阻塞十分困难。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-36507-0
Eloot, Sunny; Mertens, Tom; Josipovic, Iván; Konings, Joke; Glorieux, Griet; Fredenburgh, Laura E; Roest, Mark; Acosta, Rolando; De Somer, Filip; Marin, Ethan P; Boone, Matthieu N; Van Biesen, Wim; Vanommeslaeghe, Floris
发表日期：2026
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HDL Nanodiscs Loaded with Liver X Receptor Agonist Decreases Tumor Burden and Mediates Long-term Survival in Mouse Glioma Model.

载有肝X受体激动剂的HDL纳米盘可降低小鼠胶质瘤模型的肿瘤负荷并促进其长期存活

期刊:Small
影响因子:12.1
doi:10.1002/smll.202307097
Halseth Troy A, Mujeeb Anzar A, Liu Lisha, Banerjee Kaushik, Lang Nigel, Hollon Todd, Yu Minzhi, Vander Roest Mark, Mei Ling, He Hongliang, Sheth Maya, Castro Maria G, Schwendeman Anna
肿瘤
胶质瘤
Mouse
肿瘤免疫
发表日期：2025
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Remote loading of an autoantigen in PLGA nanoparticles for the treatment of multiple sclerosis

将自身抗原远程加载到PLGA纳米颗粒中用于治疗多发性硬化症

期刊:Journal of Controlled Release
影响因子:11.5
doi:10.1016/j.jconrel.2025.114298
Din, Corrine; Xu, Jin; Roest, Mark Vander; Dobson, Hannah E; Olsen, Karl F; Kim, April; Ju, Helen H; Schwendeman, Anna; Moon, James J; Schwendeman, Steven P
神经科学
多发性硬化症
发表日期：2025
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No correlation between thrombin generation and emicizumab levels: implications for monitoring emicizumab therapy

凝血酶生成与艾美赛珠单抗水平之间无相关性：对监测艾美赛珠单抗治疗的意义

期刊:Research and Practice in Thrombosis and Haemostasis
影响因子:3.4
doi:10.1016/j.rpth.2024.102658
van der Zwet, Konrad; Roest, Mark; Huskens, Dana; Schutgens, Roger E G; van Vulpen, Lize F D; Fischer, Kathelijn; Urbanus, Rolf T
发表日期：2025
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Role of inflammation and haemostasis on aetiology and prognosis in young patients with ischaemic stroke: study protocol of the Observational Dutch Young Symptomatic StrokE study-EXTended (ODYSSEY-nEXT) - a multicentre prospective cohort study

炎症和止血在年轻缺血性卒中患者病因和预后中的作用：荷兰青年症状性卒中观察研究扩展版（ODYSSEY-nEXT）的研究方案——一项多中心前瞻性队列研究

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2024-096330
Spiegelenberg, Janneke P; Verburgt, Esmée; den Hertog, Heleen; de Laat, Karlijn F; van Rooij, Frank G; van Uden, Inge W M; Arntz, Renate M; van den Wijngaard, Ido R; Kessels, Roy P C; Piai, Vitória; van der Kolk, Anja; Roest, Mark; de Laat, Bas; Middeldorp, Saskia; Tuladhar, Anil; Leentjens, Jenneke; de Leeuw, Frank-Erik
炎症/感染
炎症
发表日期：2025
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HDL Nanodiscs Loaded with Liver X Receptor Agonist Decreases Tumor Burden and Mediates Long-term Survival in Mouse Glioma Model

负载肝X受体激动剂的高密度脂蛋白纳米盘可降低小鼠胶质瘤模型的肿瘤负荷并延长其长期生存期。

期刊:
影响因子:
doi:10.1101/2025.04.01.646644
Halseth, Troy A; Mujeeb, Anzar A; Liu, Lisha; Banerjee, Kaushik; Lang, Nigel; Hollon, Todd; Yu, Minzhi; Roest, Mark Vander; Mei, Ling; He, Hongliang; Sheth, Maya; Castro, Maria G; Schwendeman, Anna
肿瘤
肿瘤免疫
信号转导
胶质瘤
Mouse
发表日期：2025
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Procoagulant off-target effect of the direct oral anticoagulant reversal agent Andexanet alfa

直接口服抗凝血逆转剂安德沙奈特α的促凝血脱靶效应

期刊:
影响因子:
doi:10.1016/j.bvth.2025.100100
Hoornstra, Ischa M S; Zhao, Junxiong; Middelveld, Harmen; Sun, Siyu; Schönichen, Claudia; Heemskerk, Johan W M; Stragier, Hendrik; Heylen, René; de Laat, Bas; Roest, Mark
发表日期：2025
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Crucial roles of red blood cells and platelets in whole blood thrombin generation

红细胞和血小板在全血凝血酶生成中的关键作用

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2023010027
Sun, Siyu; Campello, Elena; Zou, Jinmi; Konings, Joke; Huskens, Dana; Wan, Jun; Fernández, Delia I; Reutelingsperger, Chris P M; Ten Cate, Hugo; Toffanin, Serena; Bulato, Cristiana; de Groot, Philip G; de Laat, Bas; Simioni, Paolo; Heemskerk, Johan W M; Roest, Mark
血小板
细胞生物学
红细胞
发表日期：2023
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Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery.

靶向丝氨酸蛋白酶抑制剂（TaSER）：一种双重作用的抗血栓药物，靶向血小板递送丝氨酸蛋白酶抑制剂

期刊:Journal of Thrombosis and Haemostasis
影响因子:5
doi:10.1111/jth.15554
Sanrattana Wariya, Smits Simone, Barendrecht Arjan D, van Kleef Nadine D, El Otmani Hinde, Zivkovic Minka, Roest Mark, Renné Thomas, Clark Chantal C, de Maat Steven, Maas Coen
其它
药物研究
发表日期：2022
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