日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An in vitro model demonstrating homeostatic interactions between reconstructed human gingiva and a saliva-derived multispecies biofilm

一种体外模型,展示重建的人类牙龈和唾液衍生的多物种生物膜之间的稳态相互作用

Lin Shang, Sanne Roffel, Vera Slomka, Eleanor M D'Agostino, Aline Metris, Mark J Buijs, Bernd W Brandt, Dongmei Deng, Susan Gibbs, Bastiaan P Krom

Diminished osteoprotegerin production by gingival fibroblasts from periodontitis patients is associated with their reduced ability to suppress osteoclastogenesis

牙周炎患者牙龈成纤维细胞中骨保护素生成减少与其抑制破骨细胞生成的能力下降有关。

Nieboga, Elwira; Drzazga, Kamila; Plonczynska, Alicja; Drapala, Dominika M; Schuster, Aureliusz; Melnykova, Mariia; Skawska, Julia; Zajdel, Michal; Kantorowicz, Malgorzata; Roffel, Sanne; Cichy, Joanna; Czesnikiewicz-Guzik, Marta; Kaczmarzyk, Tomasz; Gibbs, Susan; Potempa, Jan; Grabiec, Aleksander M

In vitro cytotoxicity (irritant potency) of toothpaste ingredients.

牙膏成分的体外细胞毒性(刺激效力)

Kasi Shaira R, Roffel Sanne, Özcan Mutlu, Gibbs Susan, Feilzer Albert J

Incorporation of iPSCs together with TERT-immortalized keratinocytes and fibroblasts into reconstructed human gingiva enhances phenotype of gingival epithelium.

将 iPSCs 与 TERT 永生化角质形成细胞和成纤维细胞一起整合到重建的人类牙龈中,可增强牙龈上皮的表型

Brueske Lisa-Lee, Roffel Sanne, Beekhuis-Hoekstra Stephanie, de Vries Helga E, Gibbs Susan

The application of Phase 0 and microtracer approaches in early clinical development: past, present, and future

0期临床试验和微示踪剂方法在早期临床开发中的应用:过去、现在和未来

Roffel, A F; van Hoogdalem, E-J

Nickel allergy is associated with a broad spectrum cytokine response

镍过敏与广谱细胞因子反应有关

Niels P J De Graaf, Sanne Roffel, Susan Gibbs, Cees J Kleverlaan, Marta Lopez Gonzalez, Thomas Rustemeyer, Albert J Feilzer, Hetty J Bontkes0

A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion

重建人类皮肤黑色素瘤模型,用于研究促进黑色素瘤早期生长和侵袭的免疫调节和血管生成机制

Elisabetta Michielon, Marta López González, Dorian A Stolk, Joeke G C Stolwijk, Sanne Roffel, Taco Waaijman, Sinéad M Lougheed, Tanja D de Gruijl, Susan Gibbs

Stable reconstructed human gingiva-microbe interaction model: Differential response to commensals and pathogens

稳定的重建人类牙龈-微生物相互作用模型:对共生菌和病原菌的不同反应

Zhang, Yan; Shang, Lin; Roffel, Sanne; Krom, Bastiaan P; Gibbs, Susan; Deng, Dongmei

Strategic, feasibility, economic, and cultural aspects of phase 0 approaches: Is it time to change the drug development process in order to increase productivity?

期方法的战略、可行性、经济和文化方面:现在是时候改变药物开发流程以提高生产力了吗?

Burt, Tal; Roffel, Ad F; Langer, Oliver; Anderson, Kirsten; DiMasi, Joseph

Saliva-derived microcosm biofilms grown on different oral surfaces in vitro

体外在不同口腔表面生长的唾液微生物膜

Xiaolan Li #, Lin Shang #, Bernd W Brandt, Mark J Buijs, Sanne Roffel, Cor van Loveren, Wim Crielaard, Susan Gibbs, Dong Mei Deng