日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein

有效表征小分子成像配体在淀粉样β蛋白、tau 蛋白和 alpha-突触核蛋白上的多个结合位点

Jens Sobek, Junhao Li, Benjamin F Combes, Juan A Gerez, Martin T Henrich, Fanni F Geibl, Peter R Nilsson, Kuangyu Shi, Axel Rominger, Wolfgang H Oertel, Roger M Nitsch, Agneta Nordberg, Hans Ågren, Ruiqing Ni2

A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

针对病理性 IAPP 聚集体的人类抗体可保护 2 型糖尿病模型中的 β 细胞

Fabian Wirth #, Fabrice D Heitz #, Christine Seeger, Ioana Combaluzier, Karin Breu, Heather C Denroche, Julien Thevenet, Melania Osto, Paolo Arosio, Julie Kerr-Conte, C Bruce Verchere, François Pattou, Thomas A Lutz, Marc Y Donath, Christoph Hock, Roger M Nitsch, Jan Grimm

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

用于体内应用的无异种诱导多能干细胞来源的神经祖细胞

Ruslan Rust, Rebecca Z Weber, Melanie Generali, Debora Kehl, Chantal Bodenmann, Daniela Uhr, Debora Wanner, Kathrin J Zürcher, Hirohide Saito, Simon P Hoerstrup, Roger M Nitsch, Christian Tackenberg

APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes

APOE2、E3 和 E4 对同源 iPSC 衍生星形胶质细胞的细胞稳态、胆固醇代谢和炎症反应具有不同的调节作用。

Sherida M de Leeuw ,Aron W T Kirschner ,Karina Lindner ,Ruslan Rust ,Vanessa Budny ,Witold E Wolski ,Anne-Claude Gavin ,Roger M Nitsch ,Christian Tackenberg

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

针对转甲状腺素淀粉样蛋白的人类抗体通过吞噬免疫细胞去除心脏淀粉样蛋白

Aubin Michalon, Andreas Hagenbuch, Christian Huy, Evita Varela, Benoit Combaluzier, Thibaud Damy, Ole B Suhr, Maria J Saraiva, Christoph Hock, Roger M Nitsch, Jan Grimm

Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model

针对 RAN 蛋白的抗体疗法可挽救 C9orf72 小鼠模型中的 C9 ALS/FTD 表型

Lien Nguyen, Fabio Montrasio, Amrutha Pattamatta, Solaleh Khoramian Tusi, Olgert Bardhi, Kevin D Meyer, Lindsey Hayes, Katsuya Nakamura, Monica Banez-Coronel, Alyssa Coyne, Shu Guo, Lauren A Laboissonniere, Yuanzheng Gu, Saravanakumar Narayanan, Benjamin Smith, Roger M Nitsch, Mark W Kankel, Mia Rus

Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation

人类淀粉样β蛋白(1-42)的寡聚形式可抑制抗原呈递

Christoph Gericke, Anna Mallone, Britta Engelhardt, Roger M Nitsch, Maria Teresa Ferretti

Fe65 is the sole member of its family that mediates transcription regulated by the amyloid precursor protein

Fe65 是其家族中唯一介导由淀粉样蛋白前体调控的转录的成员

Sabine Probst, Maik Krüger, Larissa Kägi, Sarina Thöni, Daniel Schuppli, Roger M Nitsch, Uwe Konietzko

A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

脑血管生长、成熟和损伤自动分析实用指南

Ruslan Rust, Tunahan Kirabali, Lisa Grönnert, Berre Dogancay, Yanuar D P Limasale, Andrea Meinhardt, Carsten Werner, Bàrbara Laviña, Luka Kulic, Roger M Nitsch, Christian Tackenberg, Martin E Schwab

Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity

赖氨酸乙酰转移酶 Tip60 乙酰化 APP 接头蛋白 Fe65 以增加其转录活性

Sabine Probst, Florian Riese, Larissa Kägi, Maik Krüger, Natalie Russi, Roger M Nitsch, Uwe Konietzko