日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sterically induced conformational restriction: Discovery and preclinical evaluation of novel pyrrolo[3,2-d]pyrimidines as microtubule targeting agents

空间位阻诱导的构象限制:新型吡咯并[3,2-d]嘧啶类化合物作为微管靶向剂的发现和临床前评价

Pavana, Roheeth Kumar; Shah, Khushbu; Gentile, Taylor; Dybdal-Hargreaves, Nicholas F; Risinger, April L; Mooberry, Susan L; Hamel, Ernest; Gangjee, Aleem

Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents

发现并进行临床前评估7-苄基-N-(取代)-吡咯并[3,2-d]嘧啶-4-胺类化合物作为具有微管靶向作用和三重血管激酶抑制作用的单药抗肿瘤药物

Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem