日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Complete inhibition of β-tryptase by tetramer dissociation and active site allostery due to a single antibody residue

单个抗体残基通过四聚体解离和活性位点变构作用完全抑制β-胰蛋白酶

Maun, Henry R; Azumaya, Caleigh M; Walters, Benjamin T; Vij, Rajesh; Morando, Ashley; Loyet, Kelly M; Koerber, James T; Rohou, Alexis; Lazarus, Robert A

Correction: Basket trials in rare diseases: a systematic review of current practices, methodological challenges, and future directions

更正:罕见病篮子试验:当前实践、方法学挑战和未来方向的系统性综述

Khazen, Wael; Corriol-Rohou, Solange; Evangelista, Teresinha; Valent, Arnaud; Abbas, Sarah; Nissan, Xavier; Mejat, Alexandre

Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture

二聚体NINJ1的自身抑制可防止质膜破裂

Sergei Pourmal # ,Melissa E Truong # ,Matthew C Johnson # ,Ying Yang # ,Lijuan Zhou ,Kamela Alegre ,Irma B Stowe ,Shalini Gupta ,Phoebe A Chen ,Yingnan Zhang ,Alexis Rohou ,Kim Newton ,Nobuhiko Kayagaki ,Vishva M Dixit ,Ishan Deshpande

Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM

二硫键约束的Fab片段克服了高分辨率单颗粒冷冻电镜成像的目标尺寸限制。

Kung, Jennifer E; Johnson, Matthew C; Tegunov, Dimitry; Jao, Christine C; Wu, Ping; Oh, Angela; Lin, May; Daria, Jose M; Koth, Christopher M; Arthur, Christopher P; Rohou, Alexis; Sudhamsu, Jawahar

Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera.

VHL募集嵌合体通过化学方法诱导内质网应激传感器IRE1的降解。

Du Jin, Villemure Elisia, Johnson Matthew, Azumaya Caleigh, Gaspar Catarina J, Marsters Scot, Lawrence David, Foster Scott, Rohou Alexis, Cheung Tommy K, Rose Christopher M, Garner Thomas, Ro Soo, Clark Kevin, Beresini Maureen H, Braun Marie-Gabrielle, Rudolph Joachim, Hsu Peter, Ashkenazi Avi

Regulatory Interactions and Learnings-RADIAL the Trials@Home Proof-of-Concept Trial on Decentralization

监管互动与经验教训——RADIAL:居家试验去中心化概念验证试验

Gardarsdottir, Helga; Traore, Hamidou; Huntley, Kate; Mistry, Dinesh; de Jong, Amos J; Legathe, Agnes; de Smedt, Tim; Askin, Scott; Heath, Megan; Corriol-Rohou, Solange; Lagerwaard, Bart; Zuidgeest, Mira G P

Basket trials in rare diseases: a systematic review of current practices, methodological challenges, and future directions

罕见病篮子试验:当前实践、方法学挑战和未来方向的系统性综述

Khazen, Wael; Corriol-Rohou, Solange; Evangelista, Teresinha; Valent, Arnaud; Abbas, Sarah; Nissan, Xavier; Mejat, Alexandre

Large-scale single-molecule analysis of tau proteoforms

tau蛋白异构体的大规模单分子分析

Joly, J; Budamagunta, V; Zhang, Z; Nortman, B; Jouzi, M; Bhatnagar, R; Egertson, J D; Flaster, M E; Grothe, R; Guha, S; Kaneshige, K; McVey, K; Nelson, N; Perera, R T; Tan, S J; Trinh, T; Arnott, D; Lipka, J; Pandya, N J; Rougé, L; Wendorff, T J; Kirkpatrick, D S; Rohou, A; Butler, D C; Lotz, S; Forton, A; Sartori, E R; Schwarz, J E; Brereton, P S; Chen, K; Darcy, M A; Golnabi, H R; Hartley, R; Indermuhl, P F; Inman, C E; Jin, K M; Katsyuk, S; Kota, R; Lowry, B; Menger, J C; Miller, D A; Newman, M R; Ogunyemi, A; Robinson, J K; Steiner, N; Sun, J; Tabakman, S; Wang, L; Wang, Z; Wilcox, S K; Kapp, G T; Patel, S; Temple, S; Bertucci, T; Blanchard, J; Huhmer, A; Sankar, S; Juneau, K; Mallick, P

Gender differences in self-assessed performance and stress level during training of basic interventional radiology maneuvers

性别差异在基础介入放射学操作训练中的自我评估表现和压力水平方面

Reder, Sebastian R; Rohou, Annaig; Keric, Naureen; Beiser, Katja U; Othman, Ahmed E; Abello Mercado, Mario Alberto; Altmann, Sebastian; Petrowski, Katja; Brockmann, Marc A; Brockmann, Carolin

Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40

利用天然存在的蛋白笼铁蛋白来调节 OX40 的内在激动作用

Whitney Shatz-Binder, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar Kalia