Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.
HER2 突变的计算和功能分析揭示了变构激活机制和改变的药理效应
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-21-0940
Ishiyama Noboru, O'Connor Matthew, Salomatov Andrei, Romashko Darlene, Thakur Shalabh, Mentes Ahmet, Hopkins Julia F, Frampton Garrett M, Albacker Lee A, Kohlmann Anna, Roberts Christopher, Buck Elizabeth