Immunization with full-length TprC variants induces a broad response to surface-exposed epitopes of the Treponema pallidum repeat protein family and is partially protective in the rabbit model of syphilis
用全长TprC变体进行免疫接种可诱导针对梅毒螺旋体重复蛋白家族表面暴露表位的广泛免疫应答,并在兔梅毒模型中具有部分保护作用。
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影响因子:
doi:10.1016/j.vaccine.2025.127406
Giacani, Lorenzo; Romeis, Emily; Haynes, Austin; Molini, Barbara J; Tantalo, Lauren C; Xu, Linda H; Trejos, Aldo T; Keane, Jessica; Mohamed, Zakriye; Armstrong, Thaddeus D; Wieland, Benjamin A; Phung, Quynh; Vyshenska, Dariia; Campbell, Victoria L; Godornes, Charmie; Koelle, David M; Reid, Tara B; Wang, Yang; Vorobieva, Anastassia A; Wald, Anna; Lieberman, Nicole A P; Greninger, Alexander L