日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties

PTC299 是一种新型强效二氢乳清酸脱氢酶抑制剂,具有良好的药物特性,可用于治疗血液系统恶性肿瘤

Liangxian Cao, Marla Weetall, Christopher Trotta, Katherine Cintron, Jiyuan Ma, Min Jung Kim, Bansri Furia, Charles Romfo, Jason D Graci, Wencheng Li, Joshua Du, Josephine Sheedy, Jean Hedrick, Nicole Risher, Shirley Yeh, Hongyan Qi, Tamil Arasu, Seongwoo Hwang, William Lennox, Ronald Kong, Janet Pe

Exonic splicing enhancers in fission yeast: functional conservation demonstrates an early evolutionary origin

裂殖酵母外显子剪接增强子:功能保守性表明其起源于早期进化阶段

Webb, Christopher J; Romfo, Charles M; van Heeckeren, Willem J; Wise, Jo Ann

Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo

对突变表型和剪接缺陷的分析表明,必需剪接因子U2AF的大亚基和小亚基在体内存在功能性协同作用。

Webb, Christopher J; Lakhe-Reddy, Sujata; Romfo, Charles M; Wise, Jo Ann