日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Promiscuity of Squalene Synthase-Like Enzyme: Dehydrosqualene Synthase, a Natural Squalene Hyperproducer?

角鲨烯合酶样酶的混杂性:脱氢角鲨烯合酶,一种天然的角鲨烯高产量者?

Zheng Guan, Yafeng Song, Marcel de Vries, Hjalmar Permentier, Pieter Tepper, Ronald van Merkerk, Rita Setroikromo, Wim J Quax

Tailored photoenzymatic systems for selective reduction of aliphatic and aromatic nitro compounds fueled by light

利用光能选择性还原脂肪族和芳香族硝基化合物的定制光酶系统

Alejandro Prats Luján ,Mohammad Faizan Bhat ,Sona Tsaturyan ,Ronald van Merkerk ,Haigen Fu ,Gerrit J Poelarends

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮衍生物抑制d-多巴色素互变异构酶活性并抑制非小细胞肺癌细胞增殖

Zhangping Xiao, Angelina Osipyan, Shanshan Song, Deng Chen, Reinder A Schut, Ronald van Merkerk, Petra E van der Wouden, Robbert H Cool, Wim J Quax, Barbro N Melgert, Gerrit J Poelarends, Frank J Dekker

Engineering of Multiple Modules to Improve Amorphadiene Production in Bacillus subtilis Using CRISPR-Cas9

利用 CRISPR-Cas9 对多个模块进行工程改造以提高枯草芽孢杆菌中的紫穗槐二烯产量

Yafeng Song, Siqi He, Ingy I Abdallah, Anita Jopkiewicz, Rita Setroikromo, Ronald van Merkerk, Pieter G Tepper, Wim J Quax

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

针对巨噬细胞移动抑制因子 (MIF) 的蛋白水解靶向嵌合体 (PROTAC) 在肺癌细胞中具有抗增殖活性

Zhangping Xiao, Shanshan Song, Deng Chen, Ronald van Merkerk, Petra E van der Wouden, Robbert H Cool, Wim J Quax, Gerrit J Poelarends, Barbro N Melgert, Frank J Dekker

7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor

7-羟基香豆素是基于亲和力的荧光探针,用于巨噬细胞迁移抑制因子的竞争性结合研究

Zhangping Xiao, Deng Chen, Shanshan Song, Ramon van der Vlag, Petra E van der Wouden, Ronald van Merkerk, Robbert H Cool, Anna K H Hirsch, Barbro N Melgert, Wim J Quax, Gerrit J Poelarends, Frank J Dekker

Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF)

4-取代三唑酚与巨噬细胞迁移抑制因子 (MIF) 结合的构效关系

Zhangping Xiao, Marieke Fokkens, Deng Chen, Tjie Kok, Giordano Proietti, Ronald van Merkerk, Gerrit J Poelarends, Frank J Dekker

Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering

角鲨烯合酶筛选及代谢工程在枯草芽孢杆菌中生产角鲨烯

Yafeng Song, Zheng Guan, Ronald van Merkerk, Hegar Pramastya, Ingy I Abdallah, Rita Setroikromo, Wim J Quax

Engineering the specificity of Streptococcus pyogenes sortase A by loop grafting

通过环移植改造化脓性链球菌分选酶 A 的特异性

Magdalena Wójcik, Kamil Szala, Ronald van Merkerk, Wim J Quax, Ykelien L Boersma

Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity

新型 15-脂氧合酶-1 抑制剂保护巨噬细胞免受脂多糖诱导的细胞毒性

Hao Guo, Iris C Verhoek, Gerian G H Prins, Ramon van der Vlag, Petra E van der Wouden, Ronald van Merkerk, Wim J Quax, Peter Olinga, Anna K H Hirsch, Frank J Dekker