日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Allosteric activation of the glutamate receptor mGlu2 by the serotonin receptor 5-HT(2A)

血清素受体 5-HT(2A) 对谷氨酸受体 mGlu2 的变构激活

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69939-3
Gai, Siyu; Lin, Li; Meng, Jiyong; Wu, Yichen; Xue, Li; Xu, Chanjuan; Sun, Qian; Ricarte, Adrià; Dalton, James; Renault, Pedro; Giraldo, Jesús; Pin, Jean-Philippe; Rondard, Philippe; Liu, Jianfeng
信号转导
5-HT
发表日期：2026
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Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction.

纳米抗体疗法可挽救 NMDA 受体功能低下引起的行为缺陷

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-025-09265-8
Oosterlaken Mathieu, Rogliardo Angelina, Lipina Tatiana, Lafon Pierre-André, Tsitokana Mireille Elodie, Keck Mathilde, Cahuzac Héloïse, Prieu-Sérandon Pierre, Diem Séverine, Derieux Cécile, Camberlin Célia, Lafont Chrystel, Meyer Damien, Chames Patrick, Vandermoere Franck, Marin Philippe, Prézeau Laurent, Servent Denis, Salahpour Ali, Ramsey Amy J, Bécamel Carine, Pin Jean-Philippe, Kniazeff Julie, Rondard Philippe
其它
发表日期：2025
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Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis

β-arrestin在G蛋白偶联受体内吞作用中的多重作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67156-y
Liu, Junke; Xue, Li; Ravier, Magalie A; Eshak, Floriane; Acher, Francine C; Goupil-Lamy, Anne; Cimadevila, Marta; Drube, Julia; Hoffmann, Carsten; Inoue, Asuka; Trinquet, Eric; Dupuis, Elodie; Prézeau, Laurent; Pin, Jean-Philippe; Rondard, Philippe
信号转导
发表日期：2025
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GABA-independent activation of GABA(B) receptor by mechanical forces.

机械力对 GABA(B) 受体的 GABA 非依赖性激活。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64811-2
Huo Yujia, Zhou Yiwei, Lin Li, Yang Fan, Meng Jiyong, He Feiteng, Zhang Fengfan, Song Mengdan, Shen Cangsong, Liu Yuxuan, Rondard Philippe, Xu Chanjuan, Xu X Z Shawn, Liu Jianfeng
信号转导
发表日期：2025
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Triple Labeling Resolves a GPCR Intermediate State by Using Three-Color Single Molecule FRET

三重标记法利用三色单分子FRET解析GPCR中间态

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c18364
Bonhomme, Léo; Bilgen, Ecenaz; Clerté, Caroline; Pin, Jean-Philippe; Rondard, Philippe; Margeat, Emmanuel; Lamb, Don C; Quast, Robert B
GPCR/Calcium/cAMP
RET
发表日期：2025
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Structural Basis of GABA(B) Receptor Activation during Evolution.

GABA(B)受体激活在进化过程中的结构基础

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202509440
Hou Guofei, Zhang Shenglan, Shen Cangsong, Ji Suyu, Zou Binqian, Xu Chanjuan, Li Liang, Shen Dandan, Liang Jiayin, Chen Haidi, Rondard Philippe, Deng Cheng, He Jun, Zhang Yan, Liu Jianfeng
信号转导
发表日期：2025
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TrkB receptor interacts with mGlu2 receptor and mediates antipsychotic-like effects of mGlu2 receptor activation in the mouse

TrkB 受体与 mGlu2 受体相互作用并介导小鼠中 mGlu2 受体激活的抗精神病样作用

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adg1679
Clémentine Eva Philibert, Candice Disdier, Pierre-André Lafon, Alexandre Bouyssou, Mathieu Oosterlaken, Sonya Galant, Anne Pizzoccaro, Pola Tuduri, Jeanne Ster, Jianfeng Liu, Julie Kniazeff, Jean-Philippe Pin, Philippe Rondard, Philippe Marin, Franck Vandermoere
神经
Mouse
发表日期：2024
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Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?

利用单域抗体靶向大脑：其潜力远超目前所言？

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24032632
Tsitokana, Mireille Elodie; Lafon, Pierre-André; Prézeau, Laurent; Pin, Jean-Philippe; Rondard, Philippe
神经科学
发表日期：2023
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Structural basis of the activation of metabotropic glutamate receptor 3

代谢型谷氨酸受体3激活的结构基础

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-022-00623-z
Fang, Wei; Yang, Fan; Xu, Chanjuan; Ling, Shenglong; Lin, Li; Zhou, Yingxin; Sun, Wenjing; Wang, Xiaomei; Liu, Peng; Rondard, Philippe; Shi, Pan; Pin, Jean-Philippe; Tian, Changlin; Liu, Jianfeng
信号转导
代谢
发表日期：2022
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Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

变构调节剂通过增加GPCR在活性状态下的停留时间来增强激动剂的效力。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-021-25620-5
Cao, Anne-Marinette; Quast, Robert B; Fatemi, Fataneh; Rondard, Philippe; Pin, Jean-Philippe; Margeat, Emmanuel
GPCR/Calcium/cAMP
发表日期：2021
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