The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop
R-spine 的稳定性决定了 RAF 抑制剂的耐药性:对具有 αC-β4 环插入框的致癌 BRAF 突变体的全面分析
期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.abg0390
Jiajun Yap, R N V Krishna Deepak, Zizi Tian, Wan Hwa Ng, Kah Chun Goh, Alicia Foo, Zi Heng Tee, Manju Payini Mohanam, Yuen Rong M Sim, Ufuk Degirmenci, Paula Lam, Zhongzhou Chen, Hao Fan, Jiancheng Hu