Roolf相关文献与解析，生知库 | 链接生命科学的每一步

Luisa Brock ，Lina Benzien ，Sandra Lange ，Maja Huehns ，Alexandra Runge ，Catrin Roolf ，Anett Sekora ，Gudrun Knuebel ，Hugo Murua Escobar ，Christian Junghanss ，Anna Richter

KMT2A

白血病

细胞生物学

发表日期：2025

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Abdominal venous thromboses: detection of the JAK2 p.V617F mutation by next-generation ultradeep sequencing-A prevalence study of patients in Mecklenburg-West Pomerania (2017-2021)

腹部静脉血栓：利用下一代超深度测序检测JAK2 p.V617F突变——梅克伦堡-前波美拉尼亚州患者的流行病学研究（2017-2021年）

期刊:Frontiers in Medicine

影响因子:3

doi:10.3389/fmed.2023.1344769

Henze, Larissa; Grunwald, Luise; Felser, Sabine; Witte, Maria; Grosse-Thie, Christina; Roolf, Catrin; Murua Escobar, Hugo; Junghanss, Christian

The Molecular Subtype of Adult Acute Lymphoblastic Leukemia Samples Determines the Engraftment Site and Proliferation Kinetics in Patient-Derived Xenograft Models

成人急性淋巴细胞白血病样本的分子亚型决定了患者来源的异种移植模型中的植入部位和增殖动力学

期刊:Cells

影响因子:5.1

doi:10.3390/cells11010150

Anna Richter, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Saskia Krohn, Sandra Lange, Vivien Krebs, Bjoern Schneider, Johannes Lakner, Christoph Wittke, Christoph Kiefel, Irmela Jeremias, Hugo Murua Escobar, Brigitte Vollmar, Christian Junghanss

Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse

从肿瘤复发角度对前B细胞急性淋巴细胞白血病（Pro-B-ALL）细胞系中传统化疗药物反应进行分子特征分析

期刊:Genes

影响因子:2.8

doi:10.3390/genes13071240

Gladbach, Yvonne Saara; Sklarz, Lisa-Madeleine; Roolf, Catrin; Beck, Julia; Schütz, Ekkehard; Fuellen, Georg; Junghanss, Christian; Murua Escobar, Hugo; Hamed, Mohamed

Combined Application of Pan-AKT Inhibitor MK-2206 and BCL-2 Antagonist Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia.

泛AKT抑制剂MK-2206与BCL-2拮抗剂Venetoclax联合应用于B细胞前体急性淋巴细胞白血病

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms22052771

Richter Anna, Fischer Elisabeth, Holz Clemens, Schulze Julia, Lange Sandra, Sekora Anett, Knuebel Gudrun, Henze Larissa, Roolf Catrin, Murua Escobar Hugo, Junghanss Christian

Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania

超深度靶向测序揭示腹部静脉血栓患者体细胞JAK2和MPL变异的等位基因频率较低：梅克伦堡-前波美拉尼亚州正在进行的前瞻性流行病学研究结果

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-020-00254-9

Grunwald, Luise; Grosse-Thie, Christina; Sender, Sina; Knuebel, Gudrun; Krohn, Saskia; Roolf, Catrin; Junghanss, Christian; Henze, Larissa; Murua Escobar, Hugo

Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines

PI3K 抑制剂 Idelalisib 与传统细胞抑制剂阿糖胞苷和地塞米松的结合会导致通路激活发生变化，从而诱导 B 淋巴细胞白血病细胞系的抗增殖作用

期刊:Cancer Cell International

影响因子:5.3

doi:10.1186/s12935-020-01431-4

L-M Sklarz, Y S Gladbach, M Ernst, M Hamed, C Roolf, S Sender, J Beck, E Schütz, S Fischer, S Struckmann, C Junghanss, G Fuellen, H Murua Escobar

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo

酪蛋白激酶II抑制剂CX-4945对体外和体内B细胞急性淋巴细胞白血病（B-ALL）中BCL6介导的细胞凋亡信号通路的影响

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-020-6650-9

Richter, Anna; Sender, Sina; Lenz, Annemarie; Schwarz, Rico; Hinz, Burkhard; Knuebel, Gudrun; Sekora, Anett; Murua Escobar, Hugo; Junghanss, Christian; Roolf, Catrin

PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death

PDA吲哚基马来酰亚胺通过有丝分裂死亡诱导前列腺癌细胞系的抗肿瘤作用

期刊:Frontiers in Veterinary Science

影响因子:2.9

doi:10.3389/fvets.2020.558135

Schille, Jan Torben; Nolte, Ingo; Beck, Julia; Jilani, Daria; Roolf, Catrin; Pews-Davtyan, Anahit; Rolfs, Arndt; Henze, Larissa; Beller, Matthias; Brenig, Bertram; Junghanss, Christian; Schütz, Ekkehard; Murua Escobar, Hugo

Novel Isoquinolinamine and Isoindoloquinazolinone Compounds Exhibit Antiproliferative Activity in Acute Lymphoblastic Leukemia Cells

新型异喹啉胺和异吲哚喹唑啉酮化合物对急性淋巴细胞白血病细胞表现出抗增殖活性

期刊:Biomolecules & Therapeutics

影响因子:3.2

doi:10.4062/biomolther.2018.199

Roolf, Catrin; Saleweski, Jan-Niklas; Stein, Arno; Richter, Anna; Maletzki, Claudia; Sekora, Anett; Escobar, Hugo Murua; Wu, Xiao-Feng; Beller, Matthias; Junghanss, Christian

KMT2A degradation is observed in decitabine-responsive acute lymphoblastic leukemia cells

在对地西他滨敏感的急性淋巴细胞白血病细胞中观察到KMT2A降解。

Abdominal venous thromboses: detection of the JAK2 p.V617F mutation by next-generation ultradeep sequencing-A prevalence study of patients in Mecklenburg-West Pomerania (2017-2021)

腹部静脉血栓：利用下一代超深度测序检测JAK2 p.V617F突变——梅克伦堡-前波美拉尼亚州患者的流行病学研究（2017-2021年）

The Molecular Subtype of Adult Acute Lymphoblastic Leukemia Samples Determines the Engraftment Site and Proliferation Kinetics in Patient-Derived Xenograft Models

成人急性淋巴细胞白血病样本的分子亚型决定了患者来源的异种移植模型中的植入部位和增殖动力学

Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse

从肿瘤复发角度对前B细胞急性淋巴细胞白血病（Pro-B-ALL）细胞系中传统化疗药物反应进行分子特征分析

Combined Application of Pan-AKT Inhibitor MK-2206 and BCL-2 Antagonist Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia.

泛AKT抑制剂MK-2206与BCL-2拮抗剂Venetoclax联合应用于B细胞前体急性淋巴细胞白血病

Ultradeep targeted sequencing reveals low allele frequencies of somatic JAK2 and MPL variants in patients with abdominal vein thromboses: results of an ongoing prospective prevalence study in Mecklenburg-West Pomerania

超深度靶向测序揭示腹部静脉血栓患者体细胞JAK2和MPL变异的等位基因频率较低：梅克伦堡-前波美拉尼亚州正在进行的前瞻性流行病学研究结果

Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines

PI3K 抑制剂 Idelalisib 与传统细胞抑制剂阿糖胞苷和地塞米松的结合会导致通路激活发生变化，从而诱导 B 淋巴细胞白血病细胞系的抗增殖作用

Influence of Casein kinase II inhibitor CX-4945 on BCL6-mediated apoptotic signaling in B-ALL in vitro and in vivo

酪蛋白激酶II抑制剂CX-4945对体外和体内B细胞急性淋巴细胞白血病（B-ALL）中BCL6介导的细胞凋亡信号通路的影响

PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death

PDA吲哚基马来酰亚胺通过有丝分裂死亡诱导前列腺癌细胞系的抗肿瘤作用

Novel Isoquinolinamine and Isoindoloquinazolinone Compounds Exhibit Antiproliferative Activity in Acute Lymphoblastic Leukemia Cells

新型异喹啉胺和异吲哚喹唑啉酮化合物对急性淋巴细胞白血病细胞表现出抗增殖活性