日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase

发现口服生物可利用的低分子量蛋白酪氨酸磷酸酶嘌呤类抑制剂

Stephanie M Stanford, Michael A Diaz, Robert J Ardecky, Jiwen Zou, Tarmo Roosild, Zachary J Holmes, Tiffany P Nguyen, Michael P Hedrick, Socorro Rodiles, April Guan, Stefan Grotegut, Eugenio Santelli, Thomas D Y Chung, Michael R Jackson, Nunzio Bottini, Anthony B Pinkerton

Mechanism of ligand-gated potassium efflux in bacterial pathogens

细菌病原体中配体门控钾离子外排的机制

Roosild, Tarmo P; Castronovo, Samantha; Healy, Jess; Miller, Samantha; Pliotas, Christos; Rasmussen, Tim; Bartlett, Wendy; Conway, Stuart J; Booth, Ian R

KTN (RCK) domains regulate K+ channels and transporters by controlling the dimer-hinge conformation

KTN(RCK)结构域通过控制二聚体铰链构象来调节K+通道和转运蛋白。

Roosild, Tarmo P; Castronovo, Samantha; Miller, Samantha; Li, Chan; Rasmussen, Tim; Bartlett, Wendy; Gunasekera, Banuri; Choe, Senyon; Booth, Ian R

Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy

人尿苷磷酸化酶1的结构对开发新型抑制剂以提高氟尿嘧啶类化疗治疗窗口的影响

Roosild, Tarmo P; Castronovo, Samantha; Fabbiani, Michael; Pizzorno, Giuseppe

Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins

抗FLAG M2 Fab结构域的结构及其在工程化膜蛋白稳定中的应用

Roosild, Tarmo P; Castronovo, Samantha; Choe, Senyon

Characterization of the family of Mistic homologues

Mistic同源物家族的特征描述

Roosild, Tarmo P; Vega, Mark; Castronovo, Samantha; Choe, Senyon