日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4

甘油三酯代谢控制与 APOE4 相关的炎症和微胶质细胞表型

Roxan A Stephenson ,Jordy Sepulveda ,Kory R Johnson ,Adrian Lita ,Jaanam Gopalakrishnan ,Dominic J Acri ,Alexandra Beilina ,Linling Cheng ,Linda G Yang ,Jessica T Root ,Michael E Ward ,Christian Combs ,William C Skarnes ,Mark R Cookson ,Han-Yu Shih ,Mioara Larion ,G William Rebeck ,Priyanka S Narayan

Characterization of resistance to a potent D-peptide HIV entry inhibitor

对强效 D 肽 HIV 进入抑制剂的抗性表征

Amanda R Smith, Matthew T Weinstock, Amanda E Siglin, Frank G Whitby, J Nicholas Francis, Christopher P Hill, Debra M Eckert, Michael J Root, Michael S Kay

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer

经典 Wnt 通路驱动癌症中的巨胞饮作用

Gil Redelman-Sidi, Anna Binyamin, Isabella Gaeta, Wilhelm Palm, Craig B Thompson, Paul B Romesser, Scott W Lowe, Mukta Bagul, John G Doench, David E Root, Michael S Glickman

Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer

HIV-1 Env 受体激活导致 gp41 三聚体不对称暴露

Khasnis, Mukta D; Halkidis, Konstantine; Bhardwaj, Anshul; Root, Michael J

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

Csnk1a1 抑制对急性髓系白血病具有 p53 依赖性治疗效果

Marcus Järås, Peter G Miller, Lisa P Chu, Rishi V Puram, Emma C Fink, Rebekka K Schneider, Fatima Al-Shahrour, Pablo Peña, L Jordan Breyfogle, Kimberly A Hartwell, Marie E McConkey, Glenn S Cowley, David E Root, Michael G Kharas, Ann Mullally, Benjamin L Ebert

Dual function of novel pollen coat (surface) proteins: IgE-binding capacity and proteolytic activity disrupting the airway epithelial barrier.

新型花粉外层(表面)蛋白的双重功能:IgE 结合能力和蛋白水解活性,可破坏气道上皮屏障

Bashir Mohamed Elfatih H, Ward Jason M, Cummings Matthew, Karrar Eltayeb E, Root Michael, Mohamed Abu Bekr A, Naclerio Robert M, Preuss Daphne

Polyvalent side chain peptide-synthetic polymer conjugates as HIV-1 entry inhibitors

多价侧链肽-合成聚合物缀合物作为HIV-1入侵抑制剂

Danial, Maarten; Root, Michael J; Klok, Harm-Anton

Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance

设计一种具有强抗药性屏障的强效 D 肽 HIV-1 进入抑制剂

Brett D Welch, J Nicholas Francis, Joseph S Redman, Suparna Paul, Matthew T Weinstock, Jacqueline D Reeves, Yolanda S Lie, Frank G Whitby, Debra M Eckert, Christopher P Hill, Michael J Root, Michael S Kay

Interactions of HIV-1 inhibitory peptide T20 with the gp41 N-HR coiled coil

HIV-1抑制肽T20与gp41 N-HR螺旋卷曲结构的相互作用

Champagne, Kelly; Shishido, Akira; Root, Michael J

Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection

局部应用进入抑制剂作为“抗病毒药”来预防艾滋病毒感染的性传播

Lederman, Michael M; Jump, Robin; Pilch-Cooper, Heather A; Root, Michael; Sieg, Scott F