日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The role of large immune complexes in anti-drug antibody development: a case study of anti-SARS-CoV-2 antibody therapeutics and co-administered mRNA vaccine

大型免疫复合物在抗药抗体发展中的作用:以抗SARS-CoV-2抗体疗法和联合给药的mRNA疫苗为例

Irvin, Susan C; Wang, Zhiqiang; Ganguly, Samit; Choudhary, Deepanshu; Kanagaraj, Minita; Liu, Nina; Isa, Flonza; He, Zhongqing Will; Yan, Hong; Casullo, Veronica Mas; Turner, Kenneth C; Davis, John D; Rosconi, Michael P; Torri, Albert; Partridge, Michael A

Insights into the structural differences between homo- and heterodimers enriched from a cocktail of monoclonal antibodies against SARS-CoV-2

通过对SARS-CoV-2单克隆抗体混合物中富集的同源二聚体和异源二聚体的结构差异进行深入研究

Nguyen, Jennifer B; Liu, Sophia; Yan, Yuetian; Choudhary, Deepanshu; Oberholtzer, Zachary R; Zhou, Yi; Skow, Donna J; Sheikh, Mushhood; Sandu, Cristinel; Wang, Shunhai; Li, Ning; Franklin, Matthew C; Rosconi, Michael P; Pyles, Erica A

Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

鸟苷酸环化酶受体 NPR1 激动剂抗体调节血管张力

Michael E Dunn, Aaron Kithcart, Jee Hae Kim, Andre Jo-Hao Ho, Matthew C Franklin, Annabel Romero Hernandez, Jan de Hoon, Wouter Botermans, Jonathan Meyer, Ximei Jin, Dongqin Zhang, Justin Torello, Daniel Jasewicz, Vishal Kamat, Elena Garnova, Nina Liu, Michael Rosconi, Hao Pan, Satyajit Karnik, Mich

A Tetravalent Bispecific Antibody Selectively Inhibits Diverse FGFR3 Oncogenic Variants

一种四价双特异性抗体选择性抑制多种FGFR3致癌变体

Yan Yang,Avvaru N Suhasini,Zaoli Jiang,Nina Liu,Michael Rosconi,Bojie Zhang,Yinyin Li,Drew Dudgeon,Changhyun Seong,Steven Kim,Ashique Rafique,Tammy Huang,Sangram Bhosle,Pamela Krueger,Erica Ullman,William Olson,John C Lin,Yang Shen,Christopher Daly

Covalent Inhibition of a Host-Pathogen Protein-Protein Interaction Reduces the Infectivity of Streptococcus pneumoniae

共价抑制宿主-病原体蛋白-蛋白相互作用可降低肺炎链球菌的感染性

Lyu, Yuhan; Yang, Fan; Sundaresh, Bharathi; Rosconi, Federico; van Opijnen, Tim; Gao, Jianmin

Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2

SARS-COV-2 治疗性抗体混合物中异二聚体的富集策略及初步表征

Sophia Liu, Yuetian Yan, Cody M Secor, Zachary R Oberholtzer, Donna J Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B Nguyen, Michael P Rosconi, Erica A Pyles

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

细菌泛基因组使基因必需性依赖于菌株且可进化

Federico Rosconi, Emily Rudmann #, Jien Li #, Defne Surujon, Jon Anthony, Matthew Frank, Dakota S Jones, Charles Rock, Jason W Rosch, Christopher D Johnston, Tim van Opijnen

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

抗生素敏感性靶点和耐受途径的全基因组图谱

Leshchiner, Dmitry; Rosconi, Federico; Sundaresh, Bharathi; Rudmann, Emily; Ramirez, Luisa Maria Nieto; Nishimoto, Andrew T; Wood, Stephen J; Jana, Bimal; Buján, Noemí; Li, Kaicheng; Gao, Jianmin; Frank, Matthew; Reeve, Stephanie M; Lee, Richard E; Rock, Charles O; Rosch, Jason W; van Opijnen, Tim

Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5

使用 Pozelimab(一种针对补体成分 C5 的全人抗体)抑制补体途径活化

Adrianna Latuszek, Yashu Liu, Olav Olsen, Randi Foster, Marc Cao, Irena Lovric, Ming Yuan, Nina Liu, Henry Chen, Qian Zhang, Hui Xiao, Carola Springer, George Ehrlich, Vishal Kamat, Ashique Rafique, Ying Hu, Pamela Krueger, Tammy Huang, William Poueymirou, Robert Babb, Michael P Rosconi, Marc W Rett

Herbaspirillum seropedicae Differentially Expressed Genes in Response to Iron Availability

Herbaspirillum seropedicae 对铁可用性响应的差异表达基因

Trovero, María F; Scavone, Paola; Platero, Raúl; de Souza, Emanuel M; Fabiano, Elena; Rosconi, Federico