Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria
κ阿片受体的偏向性激动剂可抑制疼痛和瘙痒,而不会引起镇静或烦躁不安。
期刊:Science Signaling
影响因子:6.6
doi:10.1126/scisignal.aai8441
Brust, Tarsis F; Morgenweck, Jenny; Kim, Susy A; Rose, Jamie H; Locke, Jason L; Schmid, Cullen L; Zhou, Lei; Stahl, Edward L; Cameron, Michael D; Scarry, Sarah M; Aubé, Jeffrey; Jones, Sara R; Martin, Thomas J; Bohn, Laura M