日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus

前列环素受体激动剂对人肺成纤维细胞增殖的抑制与细胞核内持续的 cAMP 信号有关

Maxine J Roberts, Lauren T May, Alastair C Keen, Bonan Liu, Terrance Lam, Steven J Charlton, Elizabeth M Rosethorne, Michelle L Halls

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

偏向性M1毒蕈碱受体突变小鼠为下一代药物的设计提供信息

Bradley, Sophie J; Molloy, Colin; Valuskova, Paulina; Dwomoh, Louis; Scarpa, Miriam; Rossi, Mario; Finlayson, Lisa; Svensson, Kjell A; Chernet, Eyassu; Barth, Vanessa N; Gherbi, Karolina; Sykes, David A; Wilson, Caroline A; Mistry, Rajendra; Sexton, Patrick M; Christopoulos, Arthur; Mogg, Adrian J; Rosethorne, Elizabeth M; Sakata, Shuzo; John Challiss, R A; Broad, Lisa M; Tobin, Andrew B

Airway remodeling disease: primary human structural cells and phenotypic and pathway assays to identify targets with potential to prevent or reverse remodeling

气道重塑疾病:利用原代人结构细胞、表型和通路分析来识别具有预防或逆转重塑潜力的靶点

Rosethorne, Elizabeth M; Charlton, Steven J

High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function

利用高通量诱变技术鉴定调控人前列环素(hIP)受体表达和功能的残基

Bill, Anke; Rosethorne, Elizabeth M; Kent, Toby C; Fawcett, Lindsay; Burchell, Lynn; van Diepen, Michiel T; Marelli, Anthony; Batalov, Sergey; Miraglia, Loren; Orth, Anthony P; Renaud, Nicole A; Charlton, Steven J; Gosling, Martin; Gaither, L Alex; Groot-Kormelink, Paul J

Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues

对强生7777120类似物偏向性组胺H₄受体信号传导的详细分析

Nijmeijer, S; Vischer, H F; Sirci, F; Schultes, S; Engelhardt, H; de Graaf, C; Rosethorne, E M; Charlton, S J; Leurs, R

James Lorrain Smith

詹姆斯·洛兰·史密斯

Roberts, Maxine J; Broome, Rebecca E; Kent, Toby C; Charlton, Steven J; Rosethorne, Elizabeth M; Crerar, J W