日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Novel, Long-Acting, Small Molecule PKM2 Activator and Its Potential Broad Application Against Photoreceptor Degeneration

一种新型长效小分子PKM2激活剂及其在对抗光感受器退行性疾病方面的潜在广泛应用

Warren W Pan,Katherine M Weh,Sraboni Chaudhury,Roshini Fernando,Heather Hager,Bo Wen,Krishnapriya Chinnaswamy,Jeanne A Stuckey ,Jason C Rech,Cagri G Besirli,Eric Weh,Thomas J Wubben

Metabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration

HK2 和 PKM2 同时缺失引起的代谢改变导致感光细胞功能障碍和退化

Eric Weh, Moloy Goswami, Sraboni Chaudhury, Roshini Fernando, Nick Miller, Heather Hager, Sarah Sheskey, Vikram Sharma, Thomas J Wubben, Cagri G Besirli

Development of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis

开发新型丙酮酸激酶肌肉同工酶 2(PKM2)小分子激活剂以减少感光细胞凋亡

Thomas J Wubben, Sraboni Chaudhury, Brennan T Watch, Jeanne A Stuckey, Eric Weh, Roshini Fernando, Moloy Goswami, Mercy Pawar, Jason C Rech, Cagri G Besirli

Teprotumumab Divergently Alters Fibrocyte Gene Expression: Implications for Thyroid-associated Ophthalmopathy

Teprotumumab 以不同方式改变纤维细胞基因表达:对甲状腺相关眼病的影响

Roshini Fernando, Terry J Smith

Slit2 Regulates Hyaluronan & Cytokine Synthesis in Fibrocytes: Potential Relevance to Thyroid-Associated Ophthalmopathy

Slit2 调节纤维细胞中的透明质酸和细胞因子合成:与甲状腺相关眼病的潜在相关性

Roshini Fernando, Terry J Smith

Slit2 May Underlie Divergent Induction by Thyrotropin of IL-23 and IL-12 in Human Fibrocytes

Slit2 可能是促甲状腺激素在人成纤维细胞中对 IL-23 和 IL-12 产生不同诱导作用的原因

Roshini Fernando, Stephen J Atkins, Terry J Smith

CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34+ Fibroblasts and Fibrocytes

甲状腺相关眼病患者的 CD34- 眼眶成纤维细胞调节 CD34+ 成纤维细胞和成纤维细胞中的 TNF-α 表达

Yan Lu, Stephen J Atkins, Roshini Fernando, Aaron Trierweiler, Tünde Mester, Ana Beatriz Diniz Grisolia, Pei Mou, Priscila Novaes, Terry J Smith

Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease

Slit2 调节 Graves 病眼眶浸润纤维细胞的炎症表型

Roshini Fernando, Ana Beatriz Diniz Grisolia, Yan Lu, Stephen Atkins, Terry J Smith

Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy

格雷夫斯病患者血清四氢大麻酚升高:在甲状腺相关眼病中的潜在致病作用

Roshini Fernando, Ekaterina Placzek, Edmund A Reese, Andrew T Placzek, Samantha Schwartz, Aaron Trierweiler, Leslie M Niziol, Nupur Raychaudhuri, Stephen Atkins, Thomas S Scanlan, Terry J Smith

Intersection of Chemokine and TSH Receptor Pathways in Human Fibrocytes: Emergence of CXCL-12/CXCR4 Cross Talk Potentially Relevant to Thyroid-Associated Ophthalmopathy

人类纤维细胞中趋化因子和 TSH 受体通路的交集:CXCL-12/CXCR4 串扰的出现可能与甲状腺相关眼病有关

Roshini Fernando, Stephen J Atkins, Terry J Smith