Rosinski Jim相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.

不同的错配修复复合体基因决定神经元 CAG 重复序列的扩增速率，从而驱动 HD 小鼠的选择性发病机制

影响因子:42.5

doi:10.1016/j.cell.2025.01.031

Wang Nan, Zhang Shasha, Langfelder Peter, Ramanathan Lalini, Gao Fuying, Plascencia Mary, Vaca Raymond, Gu Xiaofeng, Deng Linna, Dionisio Leonardo E, Vu Ha, Maciejewski Emily, Ernst Jason, Prasad Brinda C, Vogt Thomas F, Horvath Steve, Aaronson Jeffrey S, Rosinski Jim, Yang X William

发表日期：2025

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Modeling the effects of Huntington's disease on age-related genes reveals CXXC4 as an epigenetic target to restore health and excitability of Drd1-expressing striatal neurons

通过模拟亨廷顿病对年龄相关基因的影响，发现 CXXC4 是一个表观遗传靶点，可以恢复表达 Drd1 的纹状体神经元的健康和兴奋性。

doi:10.64898/2025.12.12.693965

Arrieta-Lobo, Maialen; Farina, Francesca; Aboy, Tamara Monteagudo; Mair, Megan; Mendoza, Cloé; Tran, Huy; Aaronson, Jeff; Rosinski, Jim; Ellerby, Lisa; Brouillet, Emmanuel; Botas, Juan; Neri, Christian; Megret, Lucile

发表日期：2025

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HGG-01. DURABLE RESPONSE TO IMMUNOTHERAPY IN AN ADOLESCENT PATEINT WITH CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY CMMRD AND SYNCHRONOUS THREE PRIMARY MALIGNANCIES

HGG-01. 一名患有先天性错配修复缺陷 (CMMRD) 和同步性三种原发性恶性肿瘤的青少年患者对免疫疗法的持久反应

doi:10.1101/2024.07.09.602815

Wang, Nan; Zhang, Shasha; Langfelder, Peter; Ramanathan, Lalini; Plascencia, Mary; Gao, Fuying; Vaca, Raymond; Gu, Xiaofeng; Deng, Linna; Dionisio, Leonardo E; Prasad, Brinda C; Vogt, Thomas; Horvath, Steve; Aaronson, Jeffrey S; Rosinski, Jim; Yang, X William; Mobarak, NAHLA Aly; Alotabi, Fahad; Balbaid, Ali Abdullah O; Shakweer, Wafa Al; Alrasheed, Rana; AlMalki, Salman Turbush A; Alharbi, Musa; AlFakeeh, Ali H

免疫/内分泌

多发性骨髓瘤

发表日期：2024

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Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

绘制白天转录组中大脑基因共表达图谱，揭示昼夜分子网络，并破译扰动基因特征

影响因子:15

doi:10.1016/j.neuron.2022.09.028

Wang Nan, Langfelder Peter, Stricos Matthew, Ramanathan Lalini, Richman Jeffrey B, Vaca Raymond, Plascencia Mary, Gu Xiaofeng, Zhang Shasha, Tamai T Katherine, Zhang Liguo, Gao Fuying, Ouk Koliane, Lu Xiang, Ivanov Leonid V, Vogt Thomas F, Lu Qing Richard, Morton A Jennifer, Colwell Christopher S, Aaronson Jeffrey S, Rosinski Jim, Horvath Steve, Yang X William

发表日期：2022

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Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice

结合特征选择和形状分析，揭示了亨廷顿病小鼠中 miRNA 调控的精确规则

期刊:BMC Bioinformatics

影响因子:3.3

doi:10.1186/s12859-020-3418-9

Mégret, Lucile; Nair, Satish Sasidharan; Dancourt, Julia; Aaronson, Jeff; Rosinski, Jim; Neri, Christian

发表日期：2020

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Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington's disease mice synchronous to symptoms

多层网络中的遗传协同作用与亨廷顿病小鼠纹状体中的细胞存活和衰老有关，且与症状同步发生

doi:10.1093/bioinformatics/btz514

Bigan, Erwan; Sasidharan Nair, Satish; Lejeune, François-Xavier; Fragnaud, Hélissande; Parmentier, Frédéric; Mégret, Lucile; Verny, Marc; Aaronson, Jeff; Rosinski, Jim; Neri, Christian

细胞生物学

发表日期：2020

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MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice

小鼠内源性亨廷顿蛋白CAG重复序列扩增的microRNA特征

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0190550

Langfelder, Peter; Gao, Fuying; Wang, Nan; Howland, David; Kwak, Seung; Vogt, Thomas F; Aaronson, Jeffrey S; Rosinski, Jim; Coppola, Giovanni; Horvath, Steve; Yang, X William

发表日期：2018

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Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease

亨廷顿病皮质纹状体功能障碍的根本原因是TrkB受体信号传导受损。

影响因子:15

doi:10.1016/j.neuron.2014.05.032

Plotkin, Joshua L; Day, Michelle; Peterson, Jayms D; Xie, Zhong; Kress, Geraldine J; Rafalovich, Igor; Kondapalli, Jyothisri; Gertler, Tracy S; Flajolet, Marc; Greengard, Paul; Stavarache, Mihaela; Kaplitt, Michael G; Rosinski, Jim; Chan, C Savio; Surmeier, D James

发表日期：2014

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