日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR

内质网应激通过抑制TMPRSS6和RNA结合蛋白HuR稳定铁调素mRNA来调控铁代谢。

Belot, Audrey; Gourbeyre, Ophélie; Palin, Anais; Rubio, Aude; Largounez, Amélie; Besson-Fournier, Céline; Latour, Chloé; Lorgouilloux, Megane; Gallitz, Inka; Montagner, Alexandra; Polizzi, Arnaud; Régnier, Marion; Smati, Sarra; Zhang, An-Sheng; Diaz-Munoz, Manuel D; Steinbicker, Andrea U; Guillou, Hervé; Roth, Marie-Paule; Coppin, Hélène; Meynard, Delphine

LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA

LJ000328 是一种新型 ALK2/3 激酶抑制剂,可抑制铁调素的表达,并显著改善 IRIDA 的表型。

Belot, Audrey; Gourbeyre, Ophélie; Fay, Alexis; Palin, Anais; Besson-Fournier, Céline; Latour, Chloé; Hopkins, Corey R; Tidmarsh, George F; Coppin, Hélène; Roth, Marie-Paule; Ritter, Matthew R; Hong, Charles C; Meynard, Delphine

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia

红细胞生成素在疟疾贫血小鼠模型中促进铁调素的抑制

Latour, Chloé; Wlodarczyk, Myriam F; Jung, Grace; Gineste, Aurélie; Blanchard, Nicolas; Ganz, Tomas; Roth, Marie-Paule; Coppin, Hélène; Kautz, Léon

Decreased Bone Formation Explains Osteoporosis in a Genetic Mouse Model of Hemochromatosiss

骨形成减少可解释血色素沉着症基因小鼠模型中的骨质疏松症

Doyard, Mathilde; Chappard, Daniel; Leroyer, Patricia; Roth, Marie-Paule; Loréal, Olivier; Guggenbuhl, Pascal

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6

由膜蛋白酶-2失活引起的缺铁性贫血依赖于功能性Bmp6的存在。

Lenoir, Anne; Deschemin, Jean-Christophe; Kautz, Léon; Ramsay, Andrew J; Roth, Marie-Paule; Lopez-Otin, Carlos; Vaulont, Sophie; Nicolas, Gaël

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

小鼠急性及慢性铁过载对铁调素调控的不同途径的证据

Ramos, Emilio; Kautz, Léon; Rodriguez, Richard; Hansen, Michael; Gabayan, Victoria; Ginzburg, Yelena; Roth, Marie-Paule; Nemeth, Elizabeta; Ganz, Tomas

Iron overload induces BMP6 expression in the liver but not in the duodenum

铁过载诱导肝脏而非十二指肠中BMP6的表达

Kautz, Léon; Besson-Fournier, Céline; Meynard, Delphine; Latour, Chloé; Roth, Marie-Paule; Coppin, Hélène

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

Bmp6 调节视网膜铁稳态,在年龄相关性黄斑变性中表达发生改变

Hadziahmetovic Majda, Song Ying, Wolkow Natalie, Iacovelli Jared, Kautz Leon, Roth Marie-Paule, Dunaief Joshua L

Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers

对铁过载敏感性不同的Hfe-/-小鼠品系肝脏和十二指肠进行基因表达谱分析:鉴定Hfe的转录调控靶点和潜在的血色素沉着症修饰因子

Coppin, Hélène; Darnaud, Valérie; Kautz, Léon; Meynard, Delphine; Aubry, Marc; Mosser, Jean; Martinez, Maria; Roth, Marie-Paule

Impact of gene expression data pre-processing on expression quantitative trait locus mapping

基因表达数据预处理对表达数量性状位点定位的影响

Labbe, Aurelie; Roth, Marie-Paule; Carmichael, Pierre-Hugues; Martinez, Maria