日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress

神经元衰老会导致剪接蛋白定位异常和细胞应激失控。

Kevin Rhine ,Rachel Li ,Hema M Kopalle ,Katherine Rothamel ,Xuezhen Ge ,Elle Epstein ,Orel Mizrahi ,Assael A Madrigal ,Hsuan-Lin Her ,Trent A Gomberg ,Anita Hermann ,Joshua L Schwartz ,Amanda J Daniels ,Uri Manor ,John Ravits ,Robert A J Signer ,Eric J Bennett ,Gene W Yeo

KIF5A binds RNA to orchestrate synaptic mRNA localization and stress granules in ALS

KIF5A通过结合RNA来调控ALS中的突触mRNA定位和应激颗粒。

Le, Phuong; Lal, Neeraj K; Xu, Shuhao; Mumford, Sara; Huang, Megan; Yang, Dong; Mizrahi, Orel; Hoover, Benjamin; Yee, Brian; Mei, Yuan; Rothamel, Katherine; Her, Hsuan-Lin; Blue, Steven M; Shneider, Neil A; Yeo, Gene W

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites.

对 SARS-CoV-2 RNA-蛋白质相互作用进行全基因组分析,揭示隐藏的调控位点

Xiang Joy S, Zhao Karen X, Tadri Laliv, Tamaru Kurt, Yee Brian A, Rothamel Katherine, Schmok Jonathan C, Mueller Jasmine R, Park Samuel S, Madrigal Assael A, McVicar Rachael N, Kwong Elizabeth M, Croker Ben A, Clark Alex E, Carlin Aaron F, Acevedo Charly, McCole Declan, O'Leary Seán E, Hai Rong, Leibel Sandra L, Yeo Gene W

Decoding protein-RNA interactions using CLIP-based methodologies

利用基于CLIP的方法解码蛋白质-RNA相互作用

Xiang, Joy S; Schafer, Danielle M; Rothamel, Katherine L; Yeo, Gene W

Large-scale map of RNA-binding protein interactomes across the mRNA life cycle

mRNA生命周期中RNA结合蛋白相互作用组的大规模图谱

Lena A Street,Katherine L Rothamel,Kristopher W Brannan,Wenhao Jin,Benjamin J Bokor,Kevin Dong,Kevin Rhine,Assael Madrigal,Norah Al-Azzam,Jenny Kim Kim,Yanzhe Ma,Darvesh Gorhe,Ahmed Abdou,Erica Wolin,Orel Mizrahi,Joshua Ahdout,Mayuresh Mujumdar,Ella Doron-Mandel,Marko Jovanovic,Gene W Yeo

Mudskipper detects combinatorial RNA binding protein interactions in multiplexed CLIP data

Mudskipper 可检测多重 CLIP 数据中的组合 RNA 结合蛋白相互作用

Her, Hsuanlin; Rothamel, Katherine L; Nguyen, Grady G; Boyle, Evan A; Yeo, Gene W

Protocol to process crosslinking and immunoprecipitation data into annotated binding sites

将交联和免疫沉淀数据处理成带注释的结合位点的方案

Xu, Shuhao; Nguyen, Grady G; Naritomi, Jack T; Kopalle, Hema M; Yee, Brian A; Rothamel, Katherine L; Boyle, Evan A; Yeo, Gene W

PAR-dCLIP: Enabling detection of RNA binding protein target transcripts bound at 5' termini through the incorporation of a decapping step.

PAR-dCLIP:通过引入脱帽步骤,实现对结合在 5' 末端的 RNA 结合蛋白靶转录本的检测

Lisy Samantha, Rothamel Katherine, Perevalova-Pinzul Yelena, Ascano Manuel

Multiplexed transcriptome discovery of RNA-binding protein binding sites by antibody-barcode eCLIP

通过抗体条形码 eCLIP 进行多重转录组发现 RNA 结合蛋白结合位点

Daniel A Lorenz, Hsuan-Lin Her, Kylie A Shen, Katie Rothamel, Kasey R Hutt, Allan C Nojadera, Stephanie C Bruns, Sergei A Manakov, Brian A Yee, Karen B Chapman, Gene W Yeo

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

超级增强子调控的RNA结合蛋白级联反应驱动胰腺癌

Corina E Antal ,Tae Gyu Oh,Stefan Aigner,En-Ching Luo,Brian A Yee,Tania Campos,Hervé Tiriac ,Katherine L Rothamel,Zhang Cheng,Henry Jiao,Allen Wang,Nasun Hah,Elizabeth Lenkiewicz,Jan C Lumibao,Morgan L Truitt,Gabriela Estepa,Ester Banayo,Senada Bashi,Edgar Esparza ,Ruben M Munoz,Jolene K Diedrich,Nicole M Sodir ,Jasmine R Mueller,Cory R Fraser ,Erkut Borazanci ,David Propper,Daniel D Von Hoff ,Christopher Liddle,Ruth T Yu,Annette R Atkins,Haiyong Han,Andrew M Lowy ,Michael T Barrett,Dannielle D Engle,Gerard I Evan,Gene W Yeo ,Michael Downes,Ronald M Evans