日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The SWI/SNF-related protein SMARCA3 is a histone H3K23 ubiquitin ligase that regulates H3K9me3 in cancer.

SWI/SNF 相关蛋白 SMARCA3 是一种组蛋白 H3K23 泛素连接酶,可调节癌症中的 H3K9me3

Akano Ifé, Hebert Jakob M, Tiedemann Rochelle L, Gao Qingzeng, Xiao Yang, Prescott Nicholas A, Liu Yanqing, Tan Kay See, Bastle Ryan M, Ramakrishnan Aarthi, Maze Ian, Sidoli Simone, Koche Richard P, Ganesh Karuna, Rothbart Scott B, David Yael

Structure-Activity Relationship Studies of DNA Methyltransferase 1 Monovalent Degraders.

DNA甲基转移酶1单价降解剂的结构-活性关系研究

Qian Chao, Lee Youngeun, Han Yulin, Zhong Yue, Zhou Jujun, Hrit Joel, Xie Ling, Chen Qin, Kaniskan H Ümit, Chen Xian, Rothbart Scott, Cheng Xiaodong, Xiong Yan, Jin Jian

Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1.

双重 EZH1/2 抑制通过靶向 H3K27me1 增强 DNMT 抑制剂在结肠癌中的疗效

Chomiak Alison A, Wiseman Ashley K, Hrit Joel, Liu Yanqing, Stransky Stephanie, Sidoli Simone, Tiedemann Rochelle L, Rothbart Scott B

Mechanisms of DNA Methylation Regulatory Function and Crosstalk with Histone Lysine Methylation

DNA甲基化调控功能机制及其与组蛋白赖氨酸甲基化的相互作用

Tibben, Bailey M; Rothbart, Scott B

Chromatin Regulation through Ubiquitin and Ubiquitin-like Histone Modifications

泛素和类泛素组蛋白修饰介导的染色质调控

Vaughan, Robert M; Kupai, Ariana; Rothbart, Scott B

Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays

利用Illumina MethylationEPIC BeadChip微阵列区分主动和被动DNA去甲基化

Tiedemann, Rochelle L; Eden, Hope E; Huang, Zhijun; Robertson, Keith D; Rothbart, Scott B

Lysine Methylation Regulators Moonlighting outside the Epigenome

赖氨酸甲基化调控因子在表观基因组之外也扮演着重要角色

Cornett, Evan M; Ferry, Laure; Defossez, Pierre-Antoine; Rothbart, Scott B

Structural basis for DNMT3A-mediated de novo DNA methylation.

DNMT3A介导的从头DNA甲基化的结构基础

Zhang Zhi-Min, Lu Rui, Wang Pengcheng, Yu Yang, Chen Dongliang, Gao Linfeng, Liu Shuo, Ji Debin, Rothbart Scott B, Wang Yinsheng, Wang Gang Greg, Song Jikui

A DNA methylation reader complex that enhances gene transcription

一种增强基因转录的DNA甲基化读取复合物

Harris, C Jake; Scheibe, Marion; Wongpalee, Somsakul Pop; Liu, Wanlu; Cornett, Evan M; Vaughan, Robert M; Li, Xueqin; Chen, Wei; Xue, Yan; Zhong, Zhenhui; Yen, Linda; Barshop, William D; Rayatpisheh, Shima; Gallego-Bartolome, Javier; Groth, Martin; Wang, Zonghua; Wohlschlegel, James A; Du, Jiamu; Rothbart, Scott B; Butter, Falk; Jacobsen, Steven E

A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex

D53抑制基序诱导TOPLESS辅阻遏物寡聚化,并促进辅阻遏物-核小体复合物的组装。

Ma, Honglei; Duan, Jingbo; Ke, Jiyuan; He, Yuanzheng; Gu, Xin; Xu, Ting-Hai; Yu, Hong; Wang, Yonghong; Brunzelle, Joseph S; Jiang, Yi; Rothbart, Scott B; Xu, H Eric; Li, Jiayang; Melcher, Karsten